Document Detail


In vitro cultivation of Treponema pallidum: a review.
MedLine Citation:
PMID:  6172213     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In vitro cultivation of Treponema pallidum would facilitate many different aspects of syphilis research. This review summarizes developments in this field that have been published since 1975. Findings are discussed in terms of treponemes and the oxygen question, treponemal metabolism involving proteins, nucleic acids, and fatty acids, and treponemal interaction with tissue culture cells. Suggested future approaches and potential problem areas pertinent to successful cultivation are discussed.
Authors:
T Fitzgerald
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Publication Detail:
Type:  In Vitro; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; Review    
Journal Detail:
Title:  Bulletin of the World Health Organization     Volume:  59     ISSN:  0042-9686     ISO Abbreviation:  Bull. World Health Organ.     Publication Date:  1981  
Date Detail:
Created Date:  1982-03-26     Completed Date:  1982-03-26     Revised Date:  2010-10-26    
Medline Journal Info:
Nlm Unique ID:  7507052     Medline TA:  Bull World Health Organ     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  787-101     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Bacterial Proteins / biosynthesis
Culture Techniques
DNA, Bacterial / biosynthesis
Oxygen Consumption
RNA, Bacterial / biosynthesis
Rabbits
Sulfhydryl Reagents / metabolism
Treponema pallidum / growth & development*,  metabolism
Grant Support
ID/Acronym/Agency:
AI 08124/AI/NIAID NIH HHS; AI 12978/AI/NIAID NIH HHS; AI 16585/AI/NIAID NIH HHS
Chemical
Reg. No./Substance:
0/Bacterial Proteins; 0/DNA, Bacterial; 0/RNA, Bacterial; 0/Sulfhydryl Reagents
Comments/Corrections

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