Document Detail

In vitro characterization of an aortic bioprosthetic valve using Doppler echocardiography and qualitative flow visualization.
MedLine Citation:
PMID:  23367452     Owner:  NLM     Status:  MEDLINE    
A 19 mm diameter prototype bioprosthetic valve mounted in a cardiac pulse duplicator was characterized using Doppler echocardiography and qualitative flow visualization at a heart rate of 72 bpm. Analysis of the flow visualization images revealed that the prototype and control valve leaflets open symmetrically but close asymmetrically. The asymmetry in the closing of the valves is likely due to the large pressure gradients across the valves and may have implications for the long term mechanical failure of the valves. The relatively high peak systolic velocity of 309.9 cm/s, which was measured in the prototype 19 mm valve, can be attributed to the small valve diameter and the high cardiac output used in the current study.
Kiran Dellimore; Iain Kemp; Reynaldo Rodriguez; Cornie Scheffer
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference     Volume:  2012     ISSN:  1557-170X     ISO Abbreviation:  Conf Proc IEEE Eng Med Biol Soc     Publication Date:  2012  
Date Detail:
Created Date:  2013-01-31     Completed Date:  2013-09-17     Revised Date:  2014-08-21    
Medline Journal Info:
Nlm Unique ID:  101243413     Medline TA:  Conf Proc IEEE Eng Med Biol Soc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  6641-4     Citation Subset:  IM    
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MeSH Terms
Aortic Valve / pathology,  physiology,  physiopathology*
Biocompatible Materials / chemistry
Cardiac Output
Computational Biology
Computer Simulation
Echocardiography, Doppler / methods*
Heart Rate
Heart Valve Prosthesis*
Prosthesis Design
Reg. No./Substance:
0/Biocompatible Materials

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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