Document Detail


In vitro assessment of the unloading and perfusion capacities of the PUCA II and the IABP.
MedLine Citation:
PMID:  15072252     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The PUCA II pump is a minimally invasive intra-arterial left ventricular assist device that can be used as an alternative for the intra-aortic balloon pump (IABP). In this study, we assessed the cardiac unloading and organ perfusion capacities of both PUCA II and IABP in an in vitro set up, consisting of a heart simulator and a silicone arterial tree, mimicking anatomical geometry and flow distribution. The IABP was positioned in the descending aorta, while the PUCA II was tested both in 'trans-aortic' and 'abdominal' positions. All devices were driven by the same Arrow AutoCat IABP driver at different pump rates. Apart from flow, arterial pressure and pulse pressure, we also calculated haemodynamic indices for myocardial oxygen supply and demand. The 'abdominal' PUCA II assist and the IABP both provide mild unloading of the heart, and a limited improvement of arterial pressure and flow. The 'trans-aortic' PUCA II assist greatly enhances flow and pressure, but does not unload the heart properly in the tested configuration.
Authors:
Stijn Vandenberghe; Patrick Segers; Hans Josemans; Jan-Paul Van Loon; Gerhard Rakhorst; Pascal Verdonck
Publication Detail:
Type:  Evaluation Studies; In Vitro; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Perfusion     Volume:  19     ISSN:  0267-6591     ISO Abbreviation:  Perfusion     Publication Date:  2004 Jan 
Date Detail:
Created Date:  2004-04-09     Completed Date:  2004-10-05     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8700166     Medline TA:  Perfusion     Country:  England    
Other Details:
Languages:  eng     Pagination:  25-32     Citation Subset:  IM    
Affiliation:
Hydraulics Laboratory, Institute Biomedical Technology, Ghent University, Belgium. stijn.vandenberghe@navier.ugent.be
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MeSH Terms
Descriptor/Qualifier:
Animals
Biological Availability
Blood Pressure
Cattle
Equipment Design
Heart / physiopathology
Heart Ventricles
Heart-Assist Devices*
Hemodynamics
Intra-Aortic Balloon Pumping / instrumentation*
Models, Biological
Myocardium / metabolism
Oxygen / blood
Perfusion / methods*
Regional Blood Flow
Chemical
Reg. No./Substance:
7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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