| In vitro antiplaque effects of a triclosan/copolymer mouthrinse. | |
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MedLine Citation:
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PMID: 2083045 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The influence of a mouthrinse containing 0.03% triclosan (2,4,4'-trichloro-2'-hydroxydiphenyl ether) and 0.25% copolymer (polyvinylmethylether maleic acid copolymer), compared to a matching placebo rinse, on in vitro plaque formation was assessed in two dynamic plaque model systems. In the controlled saliva flow cell system, the triclosan-containing rinses significantly reduced total plaque compared to the placebo rinse, with no significant differences when copolymer was removed from the active rinse formula. In the continuous culture system (chemostat flow cell model), the mean plaque was significantly reduced when compared with placebo. The results of these studies indicate that a triclosan mouthrinse, in the presence or absence of copolymer, is effective in reducing plaque in vitro. |
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Authors:
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M Williams; S Herles; S Olsen; J Afflitto; A Gaffar |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: American journal of dentistry Volume: 3 Spec No ISSN: 0894-8275 ISO Abbreviation: Am J Dent Publication Date: 1990 Sep |
Date Detail:
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Created Date: 1991-05-14 Completed Date: 1991-05-14 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8806701 Medline TA: Am J Dent Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: S53-6 Citation Subset: D |
Affiliation:
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Colage-Palmolive Technology Center, Piscataway, NJ 08854. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Bacteria
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drug effects Cells, Cultured Dental Plaque / microbiology* Humans Maleates / pharmacology* Mouthwashes / pharmacology* Polyvinyls / pharmacology* Saliva / microbiology Spectrum Analysis Triclosan / pharmacology* |
| Chemical | |
Reg. No./Substance:
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0/Maleates; 0/Mouthwashes; 0/Polyvinyls; 0/polyvinylmethoxyethylene-maleic anhydride copolymer; 3380-34-5/Triclosan |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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