Document Detail

In vitro antibacterial activity of amikacin, a new aminoglycoside, against clinical bacterial isolates from children.
MedLine Citation:
PMID:  1127131     Owner:  NLM     Status:  MEDLINE    
Four hundred and fifty-eight clinical bacterial isolates from a children's hospital were examined for antibiotic susceptibility to amikacin (BB-KS) in comparison with a number of other antibiotics by the disk diffusion and agar dilution methods. The wide spectrum of activity of amikacin against Gram-negative bacteria was confirmed; it included E. coli, Proteus species, Enterobacter species, and Pseudomonas aeruginosa. Staphylococci were highly sensitive, but other Gram-positive bacteria tested were resistant. A disk zone diameter of 10 mm effectively separated resistant form sensitive bacteria in a standard disk diffusion test.
M I Marks
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of clinical pharmacology     Volume:  15     ISSN:  0091-2700     ISO Abbreviation:  J Clin Pharmacol     Publication Date:  1975 Apr 
Date Detail:
Created Date:  1975-07-20     Completed Date:  1975-07-20     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0366372     Medline TA:  J Clin Pharmacol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  246-51     Citation Subset:  IM    
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MeSH Terms
Amikacin / pharmacology
Bacteria / drug effects*
Infection / microbiology*
Kanamycin / analogs & derivatives*
Microbial Sensitivity Tests
Reg. No./Substance:
37517-28-5/Amikacin; 59-01-8/Kanamycin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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