Document Detail


In-vitro activity of cefodizime against respiratory pathogens.
MedLine Citation:
PMID:  2127417     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The in-vitro activity of cefodizime was studied against respiratory pathogens and was compared with the activity of other beta-lactams, ciprofloxacin and erythromycin. Cefodizime displayed high activity against Haemophilus influenzae (MIC90 0.008 mg/l), Branhamella catarrhalis and Streptococcus pneumoniae (MIC90 0.5 mg/l). Klebsiella spp. were less susceptible (MIC90 2 mg/l). It was concluded that cefodizime should be a useful agent in the therapy of respiratory tract infections.
Authors:
R Wise; J M Andrews; J P Ashby
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  The Journal of antimicrobial chemotherapy     Volume:  26 Suppl C     ISSN:  0305-7453     ISO Abbreviation:  J. Antimicrob. Chemother.     Publication Date:  1990 Nov 
Date Detail:
Created Date:  1991-04-15     Completed Date:  1991-04-15     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7513617     Medline TA:  J Antimicrob Chemother     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  9-12     Citation Subset:  IM    
Affiliation:
Department of Medical Microbiology, Dudley Road Hospital, Birmingham, UK.
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MeSH Terms
Descriptor/Qualifier:
Anti-Bacterial Agents / pharmacology
Bacteria / drug effects*
Cefotaxime / analogs & derivatives*,  pharmacology
Haemophilus influenzae / drug effects
Humans
Klebsiella pneumoniae / drug effects
Microbial Sensitivity Tests
Moraxella (Branhamella) catarrhalis / drug effects
Respiratory Tract Infections / microbiology*
Streptococcus pneumoniae / drug effects
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents; 63527-52-6/Cefotaxime; 69739-16-8/cefodizime

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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