Document Detail


In vitro activities of the ketolide HMR 3647 against recent gram-positive clinical isolates and Haemophilus influenzae.
MedLine Citation:
PMID:  9687424     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The ketolide HMR 3647 (previously RU 66647) was evaluated against 2, 563 recent clinical isolates of gram-positive pathogens and 200 Haemophilus influenzae isolates. HMR 3647 was active against macrolide-resistant streptococci, including pneumococci, but was not active against macrolide- or lincosamide-resistant staphylococci. Against H. influenzae, the potency of HMR 3647 was similar to that of azithromycin.
Authors:
A L Barry; P C Fuchs; S D Brown
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Antimicrobial agents and chemotherapy     Volume:  42     ISSN:  0066-4804     ISO Abbreviation:  Antimicrob. Agents Chemother.     Publication Date:  1998 Aug 
Date Detail:
Created Date:  1998-08-24     Completed Date:  1998-08-24     Revised Date:  2013-04-18    
Medline Journal Info:
Nlm Unique ID:  0315061     Medline TA:  Antimicrob Agents Chemother     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  2138-40     Citation Subset:  IM    
Affiliation:
The Clinical Microbiology Institute, Wilsonville, Oregon 97070, USA.
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MeSH Terms
Descriptor/Qualifier:
Anti-Bacterial Agents / pharmacology*
Gram-Positive Bacteria / drug effects*
Haemophilus influenzae / drug effects*
Humans
Ketolides*
Macrolides*
Microbial Sensitivity Tests
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Ketolides; 0/Macrolides; 0/telithromycin
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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