Document Detail


In utero premature closure of the ductus arteriosus presenting as isolated right ventricular hypertrophy.
MedLine Citation:
PMID:  19886586     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: The etiology of isolated right ventricular hypertrophy (RVH) is distinct from other forms of hypertrophic cardiomyopathy. RVH is typically seen in the setting of pulmonary valve stenosis or Tetralogy of Fallot. A rare cause of isolated RVH is premature closure of the patent ductus arteriosus (PDA) in utero that results in pulmonary hypertension. This can have a range of outcomes, from spontaneous resolution to fetal demise. METHODS: This case report describes a term infant who presented with respiratory distress and striking isolated RVH, pulmonary hypertension, and no PDA. She was treated conservatively with supplemental oxygen. RESULTS: The patient was gradually weaned off oxygen over the course of two weeks and follow-up echocardiography showed resolution of her RVH and pulmonary hypertension by 14 weeks of age. CONCLUSIONS: The presentation and course of this patient with severe isolated RVH is consistent with spontaneous premature closure of the ductus arteriosus in utero.
Authors:
Webb E Long; Allen D Wilson; Shardha Srinivasan; Kimberly J Seeger; Kathleen R Maginot
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  WMJ : official publication of the State Medical Society of Wisconsin     Volume:  108     ISSN:  1098-1861     ISO Abbreviation:  WMJ     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2009-11-05     Completed Date:  2009-12-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9716054     Medline TA:  WMJ     Country:  United States    
Other Details:
Languages:  eng     Pagination:  370-2     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Division of Cardiology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792-4108, USA. wlong@uwhealth.org
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MeSH Terms
Descriptor/Qualifier:
Ductus Arteriosus, Patent / complications*,  ultrasonography
Echocardiography
Female
Humans
Hypertrophy, Right Ventricular / etiology*,  ultrasonography
Infant, Newborn
Pregnancy

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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