| In utero exposure to cocaine: a review. | |
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MedLine Citation:
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PMID: 8322077 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Cocaine is now regarded as one of the most dangerous illicit drugs available today. A disturbing trend in the pattern of cocaine use is that groups long considered unlikely to be involved in drug use, including women of childbearing age, pregnant women, the pediatric age group, fetuses, and neonates, are showing an alarming increase in cocaine exposure. Substantial data have been derived from clinical observations, clinical studies, and animal studies indicating that prenatal exposure to cocaine may have detrimental short-term and possibly long-term effects on the mother, the developing fetus, and the neonate. The effects attributed to cocaine may, however, be due to other substances (eg, alcohol) ingested by the drug-using woman, to prematurity, or to the environmental chaos in which the infant must develop. Prospective controlled studies are needed to define further the effects of cocaine as distinct from other negative influences having an impact on the developing fetus, the newborn, or the infant. |
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Authors:
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J E Ellis; L D Byrd; W R Sexson; C A Patterson-Barnett |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S.; Review |
Journal Detail:
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Title: Southern medical journal Volume: 86 ISSN: 0038-4348 ISO Abbreviation: South. Med. J. Publication Date: 1993 Jul |
Date Detail:
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Created Date: 1993-08-03 Completed Date: 1993-08-03 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0404522 Medline TA: South Med J Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 725-31 Citation Subset: AIM; IM |
Affiliation:
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Yerkes Regional Primate Research Center, Emory University, Atlanta, Ga 30322. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Central Nervous System / drug effects, embryology Cocaine / pharmacology* Embryonic and Fetal Development / drug effects* Female Humans Infant, Newborn Pregnancy Pregnancy Complications / chemically induced* Pregnancy Outcome Prenatal Exposure Delayed Effects* Substance-Related Disorders / physiopathology* |
| Grant Support | |
ID/Acronym/Agency:
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DA-01161/DA/NIDA NIH HHS; DA-06264/DA/NIDA NIH HHS; RR-00165/RR/NCRR NIH HHS |
| Chemical | |
Reg. No./Substance:
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50-36-2/Cocaine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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