Document Detail

In utero evaluation and the long-term prognosis of living infants with cystic hygroma.
MedLine Citation:
PMID:  11694746     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The aim is to evaluate the natural course and the long-term prognosis of cystic hygroma following live birth. METHODS: Of 39 cases, 12 were excluded because of either artificial termination or intrauterine treatment. 27 cases were retrospectively classified into 2 groups based on the outcome, and the clinical profiles were compared. The long-term prognosis was analyzed for live births. RESULTS: 5 (18.5%) and 22 (81.5%) cases resulted in live birth and fetal demise, respectively. Both the frequency of hydrops fetalis and the maximum size of the cyst were more significantly associated with a poor prognosis (p < 0.01). Of 5 live births, 3 cases with chromosomal or structural abnormalities were handicapped. CONCLUSIONS: Hydrops fetalis and cyst size are poor prognostic factors, and fetal chromosome and structural malformations should be taken into account when predicting the long-term prognosis.
Y Fujita; S Satoh; H Nakayama; T Taguchi; S Suita; H Nakano
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Fetal diagnosis and therapy     Volume:  16     ISSN:  1015-3837     ISO Abbreviation:  Fetal. Diagn. Ther.     Publication Date:    2001 Nov-Dec
Date Detail:
Created Date:  2001-11-05     Completed Date:  2002-01-16     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9107463     Medline TA:  Fetal Diagn Ther     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  402-6     Citation Subset:  IM    
Copyright Information:
Copyright 2001 S. Karger AG, Basel
Department of Obstetrics and Gynecology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
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MeSH Terms
Chromosome Aberrations
Gestational Age
Hydrops Fetalis / complications
Lymphangioma, Cystic / genetics,  mortality*,  ultrasonography
Ultrasonography, Prenatal

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