| In utero development of symmetric thalamic and brainstem necrosis in a preterm hydropic stillborn. | |
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MedLine Citation:
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PMID: 21073840 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Focal and symmetric necrotic lesions of the brainstem are thought to result from fetal hypotension or cardiac arrest in the perinatal period and thus occur in the course of postnatal intensive care rather than in utero. Here, we report for the first time on brainstem necrosis in a preterm stillborn demonstrating that brainstem necrosis occurs already in utero. The preterm stillborn of 28 weeks gestation of a mother that suffered from HELLP-syndrome was severely affected by a fetal hydrops with bilateral pleural effusions and lung hypoplasia. Bilateral tegmental brainstem necrosis and thalamic lesions were detected. |
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Authors:
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D P Szekessy; C Bamberg; C Blechschmidt; A M Kaindl; G Stoltenburg-Didinger |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Clinical neuropathology Volume: 29 ISSN: 0722-5091 ISO Abbreviation: Clin. Neuropathol. Publication Date: 2010 Nov-Dec |
Date Detail:
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Created Date: 2010-11-15 Completed Date: 2011-01-06 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8214420 Medline TA: Clin Neuropathol Country: Germany |
Other Details:
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Languages: eng Pagination: 365-71 Citation Subset: IM |
Affiliation:
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Department of Neonatology, Charité - Universitätsmedizin Berlin, Campus Mitte, Berlin, Germany. david.szekessy@charite.de |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Brain Stem / pathology* Female HELLP Syndrome / diagnosis Humans Hydrops Fetalis / pathology* Infant, Newborn Male Necrosis / diagnosis, pathology Pregnancy Premature Birth* Stillbirth* Thalamus / pathology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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