Document Detail

In the shadow of the wrinkle: theories.
MedLine Citation:
PMID:  22360338     Owner:  NLM     Status:  In-Data-Review    
As time passes, wrinkles typically appear. These skin depressions that become deeper and deeper draw more and more coarser lines on almost all the visible parts of aging individual's skin. They are indeed the most obvious and maybe disliked signs of skin aging, and thus, preventing and treating them are a major topic for dermo-cosmetic laboratories. However, the cause and occurrence mechanism of these simplistic looking lines are not yet fully understood. Wrinkling is thought to be a complex biophysical process resulting from repeated strains on a progressively, structurally and biochemistry altered aging skin with impaired mechanical properties. Focus is made on the specific histological features of the wrinkle compared to the surrounding aging skin. The numerous age-related changes in human skin that are supposed to be involved in wrinkling are briefly reviewed, and the current theories on wrinkle formation linked to these changes are also discussed.
Philippe Humbert; Céline Viennet; Kévin Legagneux; François Grandmottet; Sophie Robin; Thierry Oddos; Patrice Muret
Related Documents :
8075818 - Life-spanning behavioural and adrenal dysfunction induced by prenatal hypoxia in the ra...
6734768 - Age dependent changes on jejunal sugar absorption by rat in vivo.
8025248 - Age-related changes in the relative abundance of nmdar1 mrna spliced variants in the ra...
1281748 - Synaptic plasticity in the dentate gyrus of aged rats is altered after chronic nimodipi...
21157478 - Variation in childhood and adolescent obesity prevalence defined by international and c...
23114728 - Assessment of the uvulo-glossopharyngeal dimensions in patients with β-thalassemia major.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of cosmetic dermatology     Volume:  11     ISSN:  1473-2165     ISO Abbreviation:  J Cosmet Dermatol     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-02-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101130964     Medline TA:  J Cosmet Dermatol     Country:  England    
Other Details:
Languages:  eng     Pagination:  72-8     Citation Subset:  IM    
Copyright Information:
© 2012 Wiley Periodicals, Inc.
Engineering and Cutaneous Biology Team, INSERM UMR 645, IFR 133, University of Franche-Comte, Besançon, France Dermatology Department, University Hospital, Besançon, France Bioexigence, Besançon, France Johnson & Johnson Santé Beauté France, Pharmacology Department, Val de Reuil, France Clinical Pharmacology Department, University Hospital, Besançon, France.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  A single-blinded comparative study between the use of glycolic acid 70% peel and the use of topical ...
Next Document:  In the shadow of the wrinkle: experimental models.