Document Detail

In-office cup biopsies and laryngeal cytology versus operating room biopsies for the diagnosis of pharyngolaryngeal tumors: Efficacy and cost-effectiveness.
MedLine Citation:
PMID:  24889909     Owner:  NLM     Status:  Publisher    
BACKGROUND: In-office biopsy (IOB) is an effective technique to diagnose the nature of pharyngolaryngeal lesions.
METHODS: We selected patients with pharyngolaryngeal lesions suspicious for malignancy. In IOB procedures, laryngeal cytology (LC), and direct laryngoscopy biopsy (DLB) were performed, and diagnostic parameters and costs were estimated.
RESULTS: 88 patients were selected. For LC, sensitivity was 70.3% [95% CI 59.9% - 80.7%], specificity 100% with a positive predictive value of 100% and a negative predictive value of 50% [95% CI 35.2% - 64.8 %]. IOB sensitivity was 81% [95% CI 72.6% - 89.3%], specificity 100% with a positive predictive value of 100% and a negative predictive value of 20% [95% CI 2.5% - 37.5%]. At our hospital, the use of IOBs as a first approach for diagnosis saves 50,140.8 USD per annum.
CONCLUSIONS: IOB is a more affordable technique that enables histologic diagnosis of pharyngolaryngeal lesions in a large percentage of patients. Head Neck, 2014.
Felipe Castillo; Ignacio Cobeta; Rosalia Souviron; Rafael Barberá; Elena Mora; Amparo Benito; Ana Royuela
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-6-2
Journal Detail:
Title:  Head & neck     Volume:  -     ISSN:  1097-0347     ISO Abbreviation:  Head Neck     Publication Date:  2014 Jun 
Date Detail:
Created Date:  2014-6-3     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8902541     Medline TA:  Head Neck     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2014 Wiley Periodicals, Inc., A Wiley Company.
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