Document Detail

In-hospital prognostic value of hemoglobin levels on admission in patients with acute ST segment elevation myocardial infarction undergoing primary angioplasty.
MedLine Citation:
PMID:  21931965     Owner:  NLM     Status:  Publisher    
PURPOSE: Anemia is a common comorbidity in patients presenting with ST-elevation myocardial infarction (STEMI). The aim of this study was to investigate the in-hospital prognostic value of admission hemoglobin (Hb) levels in patients with acute STEMI undergoing primary percutaneous coronary intervention (p-PCI). METHODS: This is a retrospective study of 1,625 patients with STEMI stratified by quartiles of admission Hb concentration (Q1 ≤12.5 g/dl, Q2 12.6-13.8 g/dl, Q3 13.9-15.0 g/dl, Q4 ≥15.1 g/dl). Main outcome measures were in-hospital rates of all cause mortality, re-infarction, target vessel revascularization, stroke, heart failure (HF) and bleeding complications. RESULTS: The incidences of in-hospital mortality according to quartiles from Q1 to Q4 were 8.6, 3.9, 2.4 and 2.6%, respectively (p < 0.001). The incidences of major hemorrhage and HF were significantly higher in Q1, compared to the other quartiles (7.4, 1.9, 3.1, 2.8%, p < 0.001; 16.3, 8.5, 7.7, 9.8%, p < 0.001, respectively). Multiple logistic-regression analysis showed that low admission Hb level (Q1) is an independent and a potent predictor for in-hospital mortality [unadjusted odds ratio (OR): 3.84, 95% confidence interval (CI): 1.78-7.82; p < 0.001]. CONCLUSION: Lower concentrations of Hb on admission are associated with higher rates of in-hospital mortality, heart failure and major bleeding after p-PCI.
Cihan Dündar; Vecih Oduncu; Ayhan Erkol; Ali Cevat Tanalp; Dicle Sırma; Ali Karagöz; Can Yücel Karabay; Alev Kılıçgedik; Selçuk Pala; Kürşat Tigen; Akın Izgi; Cevat Kırma
Related Documents :
25475475 - Increased uptake of guideline-recommended oral antiplatelet therapy: insights from the ...
7018235 - Physiologic basis of vasodilator therapy for heart failure.
16036035 - Quality of care and outcomes in acute decompensated heart failure: the adhere registry.
1712715 - Acute and long term effects of loop diuretics in heart failure.
21186015 - Multiple organ infarctions following disseminated intravascular coagulation precipitate...
7436065 - Cpk-mb isoenzyme determinations: diagnostic and prognostic value in evaluation of blunt...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-9-20
Journal Detail:
Title:  Clinical research in cardiology : official journal of the German Cardiac Society     Volume:  -     ISSN:  1861-0692     ISO Abbreviation:  -     Publication Date:  2011 Sep 
Date Detail:
Created Date:  2011-9-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101264123     Medline TA:  Clin Res Cardiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Cardiology, Kosuyolu Heart Education and Research Hospital, Istanbul, Turkey.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Local versus general anesthesia for transfemoral aortic valve implantation.
Next Document:  Arthroplasty options in femoral-neck fracture: answers from the national registries.