Document Detail


In-a-dish: Induced pluripotent stem cells as a novel model for human diseases.
MedLine Citation:
PMID:  23281003     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Human pluripotent stem cells bring promise in regenerative medicine due to their self-renewing ability and the potential to become any cell type in the body. Moreover, pluripotent stem cells can produce specialized cell types that are affected in certain diseases, generating a new way to study cellular and molecular mechanisms involved in the disease pathology under the controlled conditions of a scientific laboratory. Thus, induced pluripotent stem cells (iPSC) are already being used to gain insights into the biological mechanisms of several human disorders. Here we review the use of iPSC as a novel tool for disease modeling in the lab. © 2012 International Society for Advancement of Cytometry.
Authors:
P C B Beltrão-Braga; G C Pignatari; F B Russo; I R Fernandes; A R Muotri
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cytometry. Part A : the journal of the International Society for Analytical Cytology     Volume:  83     ISSN:  1552-4930     ISO Abbreviation:  Cytometry A     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-01-02     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101235694     Medline TA:  Cytometry A     Country:  United States    
Other Details:
Languages:  eng     Pagination:  11-7     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 International Society for Advancement of Cytometry.
Affiliation:
Surgery Department, Stem Cell Laboratory, School of Veterinary Medicine, University of São Paulo, São Paulo, Brazil; Obstetrics Department, School of Arts, Sciences and Humanities, University of São Paulo, São Paulo, Brazil. patriciacbbbraga@usp.br.
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