| In combined first-trimester Down syndrome screening, the false-positive rate is not higher in pregnancies conceived after assisted reproduction compared with spontaneous pregnancies. | |
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MedLine Citation:
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PMID: 20723891 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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The maternal serum levels of pregnancy-associated plasma protein-A (PAPP-A) were reduced in hormonally stimulated pregnancies in the in vitro fertilization and intracytoplasmic sperm injection groups (N=176; PAPP-A: 0.82) and in the entire assisted reproduction group (N=282; PAPP-A: 0.83) as compared with controls (N=24,783; PAPP-A: 0.94). However, the false-positive rate of first-trimester combined screenings was not statistically significantly increased in assisted reproduction pregnancies after adjustment for maternal age. |
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Authors:
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Maarit Matilainen; Sini Peuhkurinen; Paivi Laitinen; Ilkka Jarvela; Laure Morin-Papunen; Marku Ryynanen |
Publication Detail:
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Type: Journal Article Date: 2010-08-19 |
Journal Detail:
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Title: Fertility and sterility Volume: 95 ISSN: 1556-5653 ISO Abbreviation: Fertil. Steril. Publication Date: 2011 Jan |
Date Detail:
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Created Date: 2010-12-20 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0372772 Medline TA: Fertil Steril Country: United States |
Other Details:
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Languages: eng Pagination: 378-81 Citation Subset: IM |
Copyright Information:
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Copyright © 2011 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved. |
Affiliation:
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Department of Obstetrics and Gynaecology, Oulu University Hospital Laboratory, Oulu University Hospital, Oulu, Finland. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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