Document Detail


In-Vivo relation between CT attenuation value and shockwave fragmentation.
MedLine Citation:
PMID:  17444784     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To use CT attenuation numbers as a means of determining the susceptibility of an artificial stone to in-vivo fragmentation with extracorporeal shockwave lithotripsy (SWL). MATERIALS AND METHODS: Four types of artificial kidney stones having different CT attenuation values were used. One randomly selected stone was implanted in the renal pelvis of a kidney of 12 young pigs and exposed in vivo to 2500 shockwaves (21 kV) using an electrohydraulic lithotripter. Bilateral nephrectomy was performed after SWL. Fragments were strained through a mesh with a 3.1-mm grid, and the debris left on the mesh was dried and weighed. Fragmentation coefficients (FCs) were associated with CT attenuation values using a statistical model. RESULTS: The relation between FC and CT number was significant, indicating that as CT attenuation increases, FC is reduced. Larger stone fragments were obtained from stones with higher CT numbers. Initial stone weight was not a significant explanation for variations in FC. CONCLUSION: The CT values could be helpful in selecting patients for SWL in the future. However, other parameters such as stone porosity, shape, and roughness also will have to be considered.
Authors:
Fernando Hurtado; Jorge Gutiérrez; Eduardo Castaño-Tostado; Julio Bustos; Enrique Mues; María Del Sol Quintero; Arturo Méndez; Achim M Loske
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of endourology / Endourological Society     Volume:  21     ISSN:  0892-7790     ISO Abbreviation:  J. Endourol.     Publication Date:  2007 Mar 
Date Detail:
Created Date:  2007-04-20     Completed Date:  2007-06-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8807503     Medline TA:  J Endourol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  343-6     Citation Subset:  IM    
Affiliation:
Nuevo Hospital Civil, Universidad de Guadalajara, Guadalajara, Jalisco, C.T. 44340 México.
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MeSH Terms
Descriptor/Qualifier:
Animals
Disease Models, Animal
Kidney Calculi / radiography*,  therapy*
Lithotripsy*
Male
Models, Biological
Models, Statistical
Nephrectomy
Swine
Tomography, X-Ray Computed*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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