Document Detail


In vivo tracking of stem cell by nanotechnologies: future prospects for mouse to human translation.
MedLine Citation:
PMID:  20846051     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Advances in stem cell research have provided important understanding of the cell biology and offered great promise for developing new strategies for tissue regeneration. Dynamic determination of stem cell migration and distribution in real time is essential for optimizing treatments in preclinical models and designing clinical protocols. Recent developments in the use of nanotechnologies have contributed to advance of the high-resolution in vivo imaging methods, including the positron emission tomography, the single-photon emission computed tomography, the magnetic resonance imaging, and microcomputed tomography. This review examines the use of nanotechnologies for stem cell tracking, the many contrast agents, and detectors that have been proposed and suggest future directions for mouse to human translation of these techniques, for both therapeutic and diagnostic purposes.
Authors:
Chiara Villa; Silvia Erratico; Paola Razini; Andrea Farini; Mirella Meregalli; Marzia Belicchi; Yvan Torrente
Publication Detail:
Type:  Journal Article     Date:  2010-10-29
Journal Detail:
Title:  Tissue engineering. Part B, Reviews     Volume:  17     ISSN:  1937-3376     ISO Abbreviation:  Tissue Eng Part B Rev     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-01-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101466660     Medline TA:  Tissue Eng Part B Rev     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1-11     Citation Subset:  IM    
Affiliation:
Stem Cell Laboratory, Department of Neurological Sciences, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Centro Dino Ferrari, Università dėgli Studi di Milano , Milano, Italy .
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