Document Detail


An in vitro comparison of the ability of three commonly used pediatric cardiopulmonary bypass circuits to filter gaseous microemboli.
MedLine Citation:
PMID:  20566585     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: The purpose of this study was to compare the ability of three commonly used pediatric cardiopulmonary bypass (CPB) circuits to filter gaseous microemboli (GME) in an in vitro model.
METHODS: Devices were tested at different levels of two specific independent variables: volume of air injected (1, 3, 5ml) and percentage of each oxygenator's rated flow (50%, 75%, 100%, 125%). The air-handling ability of each CPB circuit was determined by the Emboli Detection and Classification Quantifier (Luna Innovations Inc., Roanoke,VA).
RESULTS: At all tested conditions, the FX-05 allowed a higher percentage of GME when compared to either one or both of the other two CPB circuits. When comparing oxygenators at similar absolute flow rates, the KIDS D100/D130 CPB circuit performed worse compared to the other two CPB circuits.
CONCLUSIONS: The combination of the Baby RX-05 oxygenator and Capiox AF02 arterial line filter provides the highest level of protection from air emboli in an in vitro investigation.
Authors:
Richard W Melchior; Tami Rosenthal; Andrew C Glatz
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Publication Detail:
Type:  Journal Article     Date:  2010-06-21
Journal Detail:
Title:  Perfusion     Volume:  25     ISSN:  1477-111X     ISO Abbreviation:  Perfusion     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-08-03     Completed Date:  2010-12-10     Revised Date:  2011-05-04    
Medline Journal Info:
Nlm Unique ID:  8700166     Medline TA:  Perfusion     Country:  England    
Other Details:
Languages:  eng     Pagination:  255-63; discussion 265-6     Citation Subset:  IM    
Affiliation:
Department of Perfusion Services, Children's Hospital of Philadelphia, Philadelphia, PA, USA. melchiorr@email.chop.edu
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MeSH Terms
Descriptor/Qualifier:
Cardiopulmonary Bypass / instrumentation*
Child, Preschool
Embolism, Air / prevention & control
Extracorporeal Membrane Oxygenation / adverse effects,  instrumentation*
Hemofiltration / adverse effects,  instrumentation*
Humans
Pediatrics / instrumentation*
Comments/Corrections
Comment In:
Perfusion. 2011 Mar;26(2):167-8   [PMID:  21173038 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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