Document Detail


In Vitro antioxidant effect and inhibition of alpha-amylase of two varieties of Amaranthus caudatus seeds.
MedLine Citation:
PMID:  15930754     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This study reports on the biological properties, antioxidant and antidiabetic, of two varieties of Amaranthus caudatus seeds, Oscar blanco and Victor red. Oil, squalene and phenolic contents were also determined. Seeds of both investigated varieties were found to possess very different levels of squalene (2.2% in Oscar blanco variety and 7.5% in Victor red variety). Although the antioxidant activity of A. caudatus var. Oscar blanco and A. caudatus var. Victor red statistically did not differ significantly from each other (IC50 values of ethyl acetate extracts were 0.50 mg/ml and 0.62 mg/ml, respectively), significant differences were noticed in relation to antidiabetic activity (inhibition of alpha-amylase, EC 3.2.1.1) of methanolic extracts that showed 50.5% for A. caudatus var. Oscar blanco and 28% for A. caudatus var. Victor red at concentration of 25 microg/ml.
Authors:
Filomena Conforti; Giancarlo Statti; Monica Rosa Loizzo; Gianni Sacchetti; Ferruccio Poli; Francesco Menichini
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Biological & pharmaceutical bulletin     Volume:  28     ISSN:  0918-6158     ISO Abbreviation:  Biol. Pharm. Bull.     Publication Date:  2005 Jun 
Date Detail:
Created Date:  2005-06-02     Completed Date:  2006-01-19     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  9311984     Medline TA:  Biol Pharm Bull     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  1098-102     Citation Subset:  IM    
Affiliation:
Department of Pharmaceutical Sciences, University of Calabria, Rende, Italy. filomena.conforti@unical.it
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MeSH Terms
Descriptor/Qualifier:
Amaranthus*
Animals
Antioxidants / isolation & purification,  pharmacology*
Cattle
Plant Extracts / isolation & purification,  pharmacology
Protease Inhibitors / isolation & purification,  pharmacology
Seeds
alpha-Amylases / antagonists & inhibitors*,  metabolism
Chemical
Reg. No./Substance:
0/Antioxidants; 0/Plant Extracts; 0/Protease Inhibitors; EC 3.2.1.1/alpha-Amylases

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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