Document Detail


In vitro measurement of tissue integrity during saccular aneurysm embolizations for simulator-based training.
MedLine Citation:
PMID:  23217635     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In the domain of endovascular neurosurgery, the measurement of tissue integrity is needed for simulator-based training and for the development of new intravascular instruments and treatment techniques. In vitro evaluation of tissue manipulation can be achieved using photoelastic stress analysis and vasculature modeling with photoelastic materials. In this research we constructed two types of vasculature models of saccular aneurysms for differentiation of embolization techniques according to the respect for tissue integrity measurements based on the stress within the blood vessel model wall. In an aneurysm model with 5 mm dome diameter, embolization using MicroPlex 10 (Complex 1D, with 4 mm diameter loops), a maximum area of 3.97 mm² with stress above 1 kPa was measured. This area increased to 5.50 mm² when the dome was touched deliberately with the release mechanism of the coil, and to 4.87 mm² for an embolization using Micrusphere, (Spherical 18 Platinum Coil). In a similar way trans-cell stent-assisted coil embolization was also compared to human blood pressure simulation using a model of a wide-necked saccular aneurysm with 7 mm diameter. The area with stress above 1kPa was below 1 mm² for the pressure simulation and maximized at 3.79 mm² during the trans-cell insertion of the micro-catheter and at 8.92 mm² during the embolization. The presented results show that this measurement system is useful for identifying techniques compromising tissue integrity, comparing and studying coils and embolization techniques for a specific vasculature morphology and comparing their natural stress variations such as that produced by blood pressure.
Authors:
C Tercero; S Ikeda; K Ooe; T Fukuda; F Arai; M Negoro; I Takahashi; G Kwon
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Publication Detail:
Type:  In Vitro; Journal Article; Research Support, Non-U.S. Gov't     Date:  2012-12-03
Journal Detail:
Title:  Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences     Volume:  18     ISSN:  1591-0199     ISO Abbreviation:  Interv Neuroradiol     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-12-11     Completed Date:  2013-02-26     Revised Date:  2013-12-04    
Medline Journal Info:
Nlm Unique ID:  9602695     Medline TA:  Interv Neuroradiol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  401-12     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Aneurysm / therapy*
Birefringence
Blood Pressure
Elasticity
Embolization, Therapeutic / methods*
Endovascular Procedures / education*
Epoxy Resins
Humans
Materials Testing
Microspheres
Models, Anatomic*
Models, Cardiovascular*
Pressure
Chemical
Reg. No./Substance:
0/Epoxy Resins
Comments/Corrections

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