Document Detail


In vitro antimicrobial, antioxidant, and antispasmodic activities and the composition of the essential oil of Origanum acutidens (Hand.-Mazz.) Ietswaart.
MedLine Citation:
PMID:  20438322     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The radical scavenging, antimicrobial, and antispasmodic activities and the composition of Origanum acutidens (Hand.-Mazz.) Ietswaart (Order Labiatte) essential oil were evaluated in vitro. Gas chromatography/mass spectrometry analysis of the oil resulted in the identification of 20 compounds, representing 93.61% of the oil; carvacrol (65%) was the main component. The sample was also subjected to a screening for antioxidant activity by using the 1,1-diphenyl-2-picrylhydrazyl and beta-carotene/linoleic acid assays. The essential oil exhibited strong antioxidant activity. Using the agar disk diffusion method, antimicrobial activities of the essential oils were determined for nine microorganisms; antimicrobial activity was shown against eight of them. O. acutidens oil exhibited spontaneous contractions in rat ileum at the 100% level at 0.1 mg/mL level.
Authors:
Ismihan Goze; Ahmet Alim; Senay Akkus Cetinus; Ali Cetin; Nedim Durmus; Ahmet Turan Atas; Nilufer Vural
Publication Detail:
Type:  In Vitro; Journal Article    
Journal Detail:
Title:  Journal of medicinal food     Volume:  13     ISSN:  1557-7600     ISO Abbreviation:  J Med Food     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-06-04     Completed Date:  2010-08-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9812512     Medline TA:  J Med Food     Country:  United States    
Other Details:
Languages:  eng     Pagination:  705-9     Citation Subset:  IM    
Affiliation:
Vocational School of Health Services, Cumhuriyet University, Sivas, Turkey. igoze58@mynet.com
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MeSH Terms
Descriptor/Qualifier:
Animals
Anti-Infective Agents / analysis,  pharmacology*
Antioxidants / analysis*,  pharmacology
Bacteria / drug effects
Candida albicans / drug effects
Ileum / drug effects,  physiology
Male
Muscle Contraction / drug effects
Oils, Volatile / analysis,  pharmacology*
Origanum / chemistry*
Parasympatholytics / analysis,  pharmacology*
Plant Oils / analysis,  pharmacology*
Rats
Rats, Wistar
Chemical
Reg. No./Substance:
0/Anti-Infective Agents; 0/Antioxidants; 0/Oils, Volatile; 0/Parasympatholytics; 0/Plant Oils

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