| In Vitro Analysis of Type II Endoleaks and Aneurysm Sac Pressurization on Longitudinal Stent-Graft Displacement. | |
| | |
MedLine Citation:
|
PMID: 21861753 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
Abstract Purpose: To evaluate the effects of type II endoleaks and sac pressurization on stent-graft displacement following endovascular aneurysm repair (EVAR). Methods: Experimental silicone infrarenal aneurysm (6-cm) models were "treated" with a Talent stent-graft deployed with 20-mm proximal and distal landing zones. Inflow and outflow vessels were created as part of the silicone model to control flow into the aneurysm sac. All aneurysm models were uniform, with a diameter neck of 31 mm, a neck length of 20 mm, and iliac artery diameters of 16 mm. The aortic model was secured in a water bath to a pulsatile pump under physiological conditions; the output phase ratio (%systole/%diastole) was set at 65/35 with a pump rate of 80 beats per minute. Commercially available bifurcated stent-grafts were then displaced in vitro utilizing a linear motion apparatus attached to a force gauge. The mean arterial pressure (MAP) and pulse pressure (PP) at the aortic inflow were 60.1±3.1 and 38.3±7.8 mmHg, respectively. Peak force to cause initial stent-graft migration with and without a type II endoleak was recorded and compared. Results: In aneurysm sacs with no endoleak, the MAP and sac PP were 32±6.4 and 6±1.3 mmHg, respectively (p<0.01). In aneurysm sacs with a type II endoleak, the MAP and sac PP were 54.1±9.7 and 16.1±4.1 mmHg, respectively (p<0.02). Peak force to initiate migration was 16.0±1.41 N (range 15-18) with no endoleak vs. 23.2±2.2 N (range 20-25) in those with a type IIa endoleak and 23.5±2.5 N (range 20-26) in those with a type IIb endoleak (p<0.001). Conclusion: Type II endoleaks are associated with a significantly increased sac pressure. Increased sac pressurization from type II endoleaks results in a significantly greater force to displace a stent-graft longitudinally. Type II endoleaks may therefore inhibit migration and offer a benefit following EVAR; however, clinical correlation of these results is required. |
| | |
Authors:
|
Martyn Knowles; Tiago Pellisar; Erin H Murphy; Gregory A Stanley; Abraham F Hashmi; M Zachary Arko; Frank R Arko |
Related Documents
:
|
14513213 - Coingestion of cyclooxygenase inhibitors can worsen severe paracetamol poisoning by mid... 12754033 - Traumatic rupture of the innominate artery. 21617273 - The marfan syndrome - features, natural history and treatment options - our experiences. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists Volume: 18 ISSN: 1545-1550 ISO Abbreviation: J. Endovasc. Ther. Publication Date: 2011 Aug |
Date Detail:
|
Created Date: 2011-08-24 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 100896915 Medline TA: J Endovasc Ther Country: United States |
Other Details:
|
Languages: eng Pagination: 601-6 Citation Subset: IM |
Affiliation:
|
Department of Vascular and Endovascular Surgery, University of Texas-Southwestern, Dallas, Texas, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Endovascular management of stanford type a dissection or intramural hematoma with a distal primary e...
Next Document: Endovascular Repair of a Pancreatic Allograft Mycotic Aneurysm: Two-year Follow-up.