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MedLine Citation:
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PMID: 22532107 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Objective: Administration of atypical antipsychotics often induces significant weight gain and metabolic changes. Little is known about subjective weight-related parameters in adolescent patients. Therefore, this cross-sectional, explorative study aimed to assess these parameters and their relationship with biological weight-related parameters. Method: 74 patients (mean age: 19.9 [SD ± 2.3] years; 66.2% male) with schizophrenia under clozapine or olanzapine treatment were examined. Subjective well-being, eating behavior, body perception and social functioning were assessed, using the Three-Factor-Eating-Questionnaire, FKB-20 Body Perception Questionnaire, Subjective Well-being under Neuroleptics, Short Form and Global Assessment of Functioning. Patients' biological weight-related parameters were measured as well. Gender differences as well as associations between subjective and biological weight-related parameters were evaluated. Results: Female patients reported significantly worse negative body appraisal and physical functioning than males. An elevated BMI was associated with impaired physical functioning in females and with negative body appraisal and hunger in males. Conclusions: In our sample of young patients with schizophrenia unter treatment with atypical antipsychotics, an elevated BMI was associated with impaired physical functioning and negative body appraisal, respectively. Bearing in mind the high risk of obesity in this population, the mentioned impairments should be accounted for, especially in terms of compliance and quality of life. |
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Authors:
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Christian J Bachmann; Stefan Gebhardt; Dirk Lehr; Michael Haberhausen; Christoph Kaiser; Bärbel Otto; Frank M Theisen |
Publication Detail:
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Type: English Abstract; Journal Article |
Journal Detail:
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Title: Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie Volume: 40 ISSN: 1422-4917 ISO Abbreviation: Z Kinder Jugendpsychiatr Psychother Publication Date: 2012 May |
Date Detail:
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Created Date: 2012-04-25 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9801717 Medline TA: Z Kinder Jugendpsychiatr Psychother Country: Switzerland |
Other Details:
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Languages: ger Pagination: 151-9 Citation Subset: IM |
Affiliation:
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Klinik für Kinder- und Jugendpsychiatrie und -psychotherapie, Universitätsklinikum Gießen und Marburg gGmbH, Standort Marburg. |
Vernacular Title:
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Subjective and Biological Weight-Related Parameters. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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