Document Detail

In-hospital and 12-month postprocedural clinical outcome of coronary bifurcational lesion treatment with the endeavor stent.
MedLine Citation:
PMID:  20337860     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The zotarolimus-eluting stent (ZES) has been documented as significantly reducing restenosis and target lesion revascularization (TLR) requirement compared to bare metal stents (BMS). METHODS: In this single-centered, prospective study we sought to evaluate the short- and medium-term outcomes of ZES placement in bifurcated coronary artery lesions. Between August 2006 and December 2007, 107 consecutive patients (110 bifurcations) were recruited to have ZES placement in the lesion. The provisional T stenting (PTS) technique was used in 96.3%. Angiographic success was 100% in main vessel (MV) cases and 97.2% in that of side branch (SB). RESULTS: With a mean follow-up of 12.4 +/- 1.77 (mean +/- SD) months there were four deaths, three from cardiac cause (2.85%). There were 18 patients (19 bifurcations) requiring TLR (17.59%) for clinical reasons. The only predictor of TLR was the use diameter of ZES <or=3 mm. CONCLUSION: ZES can be used for bifurcation lesions using the PTS technique with a high rate of intraprocedural success; however, frequency of TLR is high, especially for stents with a diameter <or=3 mm.
Juan Carlos Fernández-Guerrero; Juan Herrador-Fuentes; Joaquin Sánchez-Gila; Manuel Guzmán-Herrera; Cristóbal Lozano
Publication Detail:
Type:  Journal Article     Date:  2010-03-12
Journal Detail:
Title:  Journal of interventional cardiology     Volume:  23     ISSN:  1540-8183     ISO Abbreviation:  J Interv Cardiol     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-05-14     Completed Date:  2010-08-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8907826     Medline TA:  J Interv Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  188-94     Citation Subset:  IM    
Unidad de Hemodinámica, Servicio de Cardiología, Complejo Hospitalario de Jaén, Spain.
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MeSH Terms
Aged, 80 and over
Coronary Angiography*
Coronary Disease / diagnosis,  radiography*,  therapy*
Drug-Eluting Stents* / adverse effects
Equipment Design
Follow-Up Studies
Heart Catheterization
Middle Aged
Prospective Studies
Sirolimus / administration & dosage,  analogs & derivatives*
Time Factors
Treatment Outcome
Reg. No./Substance:
0/zotarolimus; 53123-88-9/Sirolimus

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