| Imputability of heparin in heparin induced thrombocytopenia: a 10 year experience of the Centre Regional de Pharmacovigilance of Reims-Champagne Ardenne. | |
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MedLine Citation:
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PMID: 8907624 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The imputability of heparin in heparin induced thrombocytopenia (HIT) was analysed retrospectively in the chart records of 86 cases documented by the Centre Regional de Pharmacovigilance (CRPV) of Reims-Champagne Ardenne over a period of 10 years. Considerable difficulties are encountered in evaluating the degree of imputability. Chronological criteria seem to be determinant in the final imputability score, whereas semiological criteria are particularly difficult to interpret, especially as it is not yet clearly established whether biological tests should be taken into account. The method of assessment requires more precise adaptation to the specific case of HIT and could be improved by redefinition of the criteria in collaboration between pharmacologists and haematologists. |
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Authors:
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P Nguyen; M L Germain; L Sume; H Choisy |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Nouvelle revue française d'hématologie Volume: 37 ISSN: - ISO Abbreviation: Nouv Rev Fr Hematol Publication Date: 1995 |
Date Detail:
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Created Date: 1997-03-11 Completed Date: 1997-03-11 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7909092 Medline TA: Nouv Rev Fr Hematol Country: GERMANY |
Other Details:
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Languages: eng Pagination: 307-12 Citation Subset: IM |
Affiliation:
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Laboratoire Central d'Hematologie, CHU Robert Debre, France. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Evaluation Studies as Topic Female France Heparin / adverse effects* Humans Male Middle Aged Pharmacoepidemiology* Platelet Count / drug effects Reproducibility of Results Retrospective Studies Thrombocytopenia / blood*, chemically induced* |
| Chemical | |
Reg. No./Substance:
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9005-49-6/Heparin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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