Document Detail

Improving the use of human milk during and after the NICU stay.
MedLine Citation:
PMID:  20363457     Owner:  NLM     Status:  MEDLINE    
The feeding of human milk (milk from the infant's own mother; excluding donor milk) during the newborn intensive care unit (NICU) stay reduces the risk of costly and handicapping morbidities in premature infants. The mechanisms by which human milk provides this protection are varied and synergistic, and appear to change over the course of the NICU stay. The fact that these mechanisms include specific human milk components that are not present in the milk of other mammals means that human milk from the infant's mother cannot be replaced by commercial infant or donor human milk, and the feeding of human milk should be a NICU priority. Recent evidence suggests that the impact of human milk on improving infant health outcomes and reducing the risk of prematurity-specific morbidities is linked to specific critical exposure periods in the post-birth period during which the exclusive use of human milk and the avoidance of commercial formula may be most important. Similarly, there are other periods when high doses, but not necessarily exclusive use of human milk, may be important. This article reviews the concept of "dose and exposure period" for human milk feeding in the NICU to precisely measure and benchmark the amount and timing of human milk use in the NICU. The critical exposure periods when exclusive or high doses of human milk appear to have the greatest impact on specific morbidities are reviewed. Finally, the current best practices for the use of human milk during and after the NICU stay for premature infants are summarized.
Paula P Meier; Janet L Engstrom; Aloka L Patel; Briana J Jegier; Nicholas E Bruns
Related Documents :
3202087 - Studies in human lactation: milk volumes in lactating women during the onset of lactati...
10693587 - Prevalence of anemia among james bay cree infants of northern quebec.
749227 - Lead concentrations in breast milk at various stages of lactation.
12590627 - The pharmacokinetics of sertraline excretion into human breast milk: determinants of in...
6120867 - Racial differences in the etiology of abruptio placentae.
17516307 - Immediate versus delayed umbilical cord clamping in premature neonates born < 35 weeks:...
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  Clinics in perinatology     Volume:  37     ISSN:  1557-9840     ISO Abbreviation:  Clin Perinatol     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-04-05     Completed Date:  2010-07-20     Revised Date:  2014-09-20    
Medline Journal Info:
Nlm Unique ID:  7501306     Medline TA:  Clin Perinatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  217-45     Citation Subset:  IM    
Copyright Information:
Copyright 2010 Elsevier Inc. All rights reserved.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Infant Care
Infant, Extremely Low Birth Weight*
Infant, Newborn
Infant, Premature*
Intensive Care Units, Neonatal*
Milk, Human*
Patient Discharge
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Comprehensive Oxygen Management for the Prevention of Retinopathy of Prematurity: the pediatrix expe...
Next Document:  Decreasing central line associated bloodstream infection in neonatal intensive care.