Document Detail


Improving uncertainty analysis in European Union risk assessment of chemicals.
MedLine Citation:
PMID:  17695106     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Handling uncertainty in curren European Union (EU) risk assessment of new and existing substances is problematic for several reasons. The known or quantifiable sources of uncertainty are mainly considered. Uncertainty is insufficiently, explicitly communicated to risk managers and decision makers but hidden and concealed in risk quotient numbers that appear to be certain and, therefore, create a false sense of certainty and protectiveness. The new EU chemical policy legislation, REACH, is an opportunity to learn from interdisciplinary thinking in order to evolve to smart risk assessment: an assessment in which awareness and openness to uncertainty is used to produce better characterizations and evaluations of risks. In a smart risk assessment context, quantifying uncertainty is not an aim but just a productive means to refine the assessment or to find alternative solutions for the problem at stake. Guidance and examples are given on how to differentiate, assess, and use uncertainty.
Authors:
Frederik A M Verdonck; Astrid Souren; Marjolein B A van Asselt; Patrick A Van Sprang; Peter A Vanrolleghem
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Integrated environmental assessment and management     Volume:  3     ISSN:  1551-3777     ISO Abbreviation:  -     Publication Date:  2007 Jul 
Date Detail:
Created Date:  2007-08-15     Completed Date:  2007-10-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101234521     Medline TA:  Integr Environ Assess Manag     Country:  United States    
Other Details:
Languages:  eng     Pagination:  333-43     Citation Subset:  IM    
Affiliation:
Department Applied Mathematics, Biometrics and Process Control, Ghent University, Coupure Links 653, 9000 Gent, Belgium. frederik.verdonck@biomath.ugent.be
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MeSH Terms
Descriptor/Qualifier:
Chemical Industry / legislation & jurisprudence
European Union
Government Regulation
Humans
Risk Assessment* / legislation & jurisprudence
Uncertainty*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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