| Improving the reproducibility of the cyclic variation of myocardial backscatter. | |
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MedLine Citation:
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PMID: 21213569 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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The goal of myocardial tissue characterization is to augment information provided by two- and three-dimensional echocardiographic imaging, Doppler blood flow and speckle- or Doppler-derived tissue motion. Tissue characterization based on the systematic variation ofbackscattered ultrasound during the cardiac cycle ('cyclic variation') appears to be effective in characterizing both focal and diffuse myocardial pathologies. Unfortunately, comparison ofresults from different laboratories is difficult because of a lack of consistency among the several reported methods of analyzing the cyclic variation data. The goals of the present work are to present an improved method of analysis and to demonstrate that apparent disagreements are attributable primarily to the distinct approaches employed by different investigators. The improved automated method for determining the magnitude of cyclic variation utilizes binomial smoothing and an average deviation method and was validated using data acquired from 23 patients. This method illustrates a systematic means for resolving differences between laboratories. This resolution facilitates future comparisons between the cyclic variation of myocardial backscatter and measurements derived, for example, from strain-related approaches. |
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Authors:
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Christopher W Lloyd; Mark R Holland; James G Miller |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Ultrasonic imaging Volume: 32 ISSN: 0161-7346 ISO Abbreviation: Ultrason Imaging Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2011-01-07 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7909167 Medline TA: Ultrason Imaging Country: United States |
Other Details:
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Languages: eng Pagination: 243-54 Citation Subset: IM |
Affiliation:
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Department of Physics, Washington University in Saint Louis, Saint Louis, MO 63130, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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