Document Detail

Improving ovarian stimulation protocols for IVF in baboons: lessons from humans and rhesus monkeys.
MedLine Citation:
PMID:  18835115     Owner:  NLM     Status:  MEDLINE    
The aim of this review paper is to provide a scientific basis for the development of ovarian stimulation (OS) protocols for in vitro fertilization (IVF) in baboons. Firstly, the evidence available regarding OS for assisted reproduction in baboons is reviewed based on available published data, assessed by a Pub Med search of papers published between 1970 and 2008 using the following key words: baboon, assisted reproduction, IVF, embryo, oocyte. Secondly, we discuss how state-of-the-art or potentially new OS protocols used in humans and in rhesus monkeys may offer guidance for the development of standardized and reliable OS protocols for IVF in baboons. Based on this review and discussion, we conclude that more randomized trials are needed to improve standardization of OS protocols for IVF in baboons with respect to gonadotrophin type, dose, duration of stimulation, ultrasound monitoring, and time interval between ovulation trigger and oocyte retrieval.
Atunga Nyachieo; Carl Spiessens; Jason M Mwenda; Sophie Debrock; Thomas M D'Hooghe
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review     Date:  2008-08-28
Journal Detail:
Title:  Animal reproduction science     Volume:  110     ISSN:  1873-2232     ISO Abbreviation:  Anim. Reprod. Sci.     Publication Date:  2009 Feb 
Date Detail:
Created Date:  2008-12-03     Completed Date:  2009-02-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7807205     Medline TA:  Anim Reprod Sci     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  187-206     Citation Subset:  IM    
Department of Reproductive Health and Biology, Institute of Primate Research, PO Box 24481, Karen, Nairobi, Kenya.
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MeSH Terms
Fertilization in Vitro / methods,  veterinary*
Macaca mulatta
Ovulation Induction / methods,  veterinary*
Papio / physiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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