Document Detail

Improving outcome for Western Australian infants with birthweights 500-999 g.
MedLine Citation:
PMID:  7715490     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To assess changes in survival and disability in liveborn extremely low birthweight infants (500-999 g) in Western Australia, 1980-1987.
DESIGN: Cohort study comparing two periods, 1980-1983 (P1) and 1984-1987 (P2).
PARTICIPANTS: All 586 liveborn extremely low birthweight infants in WA in 1980-1987 (266 in P1, 320 in P2).
MAIN VARIABLES EXAMINED: Birthweight, place of birth, age at death, neurosensory examination findings and scores on the Griffiths Mental Development Scales or other standardised test results.
RESULTS: 482/586 infants (82%) were born at King Edward Memorial Hospital (KEMH), a level III referral centre, and a further 4% were transferred there after birth. The proportion born at KEMH increased from 78% in P1 to 86% in P2. Survival increased from 35% to 43% overall. In those below 800 g birthweight, survival doubled from 14% to 29%. There was no change in the age at death for non-survivors. Follow-up information was known for 222 of the 229 survivors at median ages of 46 months (P1) and 43 months (P2). Disability rates in infants below 800 g birthweight remained static (P1, 26%; P2, 28%), but fell in those of 800-999 g birthweight from 24% to 13%. Overall, survival free of disability increased from 26% to 34%.
CONCLUSION: Increased survival rates occurred without any increase in the rate or severity of disability in survivors.
N P French; T S Parry; S Evans
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  The Medical journal of Australia     Volume:  162     ISSN:  0025-729X     ISO Abbreviation:  Med. J. Aust.     Publication Date:  1995 Mar 
Date Detail:
Created Date:  1995-05-18     Completed Date:  1995-05-18     Revised Date:  2014-11-13    
Medline Journal Info:
Nlm Unique ID:  0400714     Medline TA:  Med J Aust     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  295-6, 298-9     Citation Subset:  IM    
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MeSH Terms
Cerebral Palsy / epidemiology
Cohort Studies
Disabled Persons / statistics & numerical data
Follow-Up Studies
Infant Mortality / trends
Infant, Low Birth Weight*
Infant, Newborn
Pregnancy Outcome / epidemiology*
Prospective Studies
Survivors / statistics & numerical data
Western Australia / epidemiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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