| Improving long-term survival of patients with acute myocardial infarction from 1977-1988 in a region of Denmark. | |
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MedLine Citation:
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PMID: 7737214 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The aim of this investigation was to study secular trends in long-term survival following myocardial infarction (MI). Five thousand one hundred and fifty-seven consecutive cases of MI in 3942 patients were recorded in a well-defined region in the study period 1977-1988. The study period ended before thrombolytic therapy was introduced in the hospital. One and 5-year survival (+/- 95% confidence limits) was 61 +/- 2% and 42 +/- 2% in 1977-1980. These figures changed to 61 +/- 2% and 44 +/- 2% in 1981-1984, and to 64 +/- 2 and 46 +/- 2% in 1985-1988. The improvement with time was statistically significant (P < 0.001). In a Cox proportional hazard model, time of infarction was an independent predictor of survival. Patients were subdivided into a high risk group suffering from either congestive heart failure or cardiac arrest during hospitalization, and a low risk group without these complications. Year of infarction was without importance in the high risk group but highly significant in the low risk group. Long-term survival following MI gradually improved prior to the introduction of thrombolytic therapy. The improvement was confined to low risk patients without cardiac arrest or congestive heart failure. |
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Authors:
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C Torp-Pedersen; P Hildebrandt; L Køber; F E Nielsen; G Jensen; T Melchior; T Joen; V Ringsdal; U Nielsen; M Ege |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: European heart journal Volume: 16 ISSN: 0195-668X ISO Abbreviation: Eur. Heart J. Publication Date: 1995 Jan |
Date Detail:
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Created Date: 1995-06-08 Completed Date: 1995-06-08 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8006263 Medline TA: Eur Heart J Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 14-20 Citation Subset: IM |
Affiliation:
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Department of Cardiology C40, Glostrup University Hospital, Denmark. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Adult Aged Aged, 80 and over Denmark / epidemiology Humans Middle Aged Myocardial Infarction / mortality*, therapy Proportional Hazards Models Retrospective Studies Risk Factors Survival Rate / trends Thrombolytic Therapy |
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