Document Detail

Improving blood pressure control in a pharmacist-managed hypertension clinic.
MedLine Citation:
PMID:  12495164     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To determine whether pharmaceutical care provided by a pharmacist-managed hypertension clinic results in better treatment outcomes when compared with traditional health care from a primary care physician. DESIGN: Prospective, controlled study SETTING: Veterans Affairs Medical Center, Philadelphia, Pennsylvania. PATIENTS: Fifty six patients with essential hypertension; 27 were randomly assigned to the intervention group and 29 to the control group. INTERVENTION: Patients in the intervention group were scheduled monthly to meet with a clinical pharmacist who made appropriate changes in prescribed drugs, adjusted dosages, and provided drug counseling in accordance with the hypertension guidelines in the sixth report of the Joint National Committee on the Detection, Evaluation, and Treatment of High Blood Pressure (JNC VI). Patients in the control group received standard care from their physicians. The study period was 6 months. MEASUREMENTS AND MAIN RESULTS: Treatment outcomes were measured by changes in compliance, blood pressure, and patient satisfaction. The Short Form-36 health survey and a patient satisfaction survey were used to measure changes in patient satisfaction, and a compliance evaluation survey measured compliance. Twenty-one (81%) patients in the intervention group attained their blood pressure goal of below 140/90 mm Hg at the completion of the study versus only eight (30%) in the control group (p < 0.0001). Of 11 patients with diabetes in the intervention group, 10 (91%) attained their blood pressure goal (< 130/80 mm Hg) versus only two (12 %) of 16 patients with diabetes in the control group (p < 0.0001). No significant differences in patient satisfaction or compliance were reported between the intervention and control groups. CONCLUSIONS: Pharmaceutical care improves blood pressure control and results in more patients with hypertension reaching their blood pressure goal.
Eva M Vivian
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Pharmacotherapy     Volume:  22     ISSN:  0277-0008     ISO Abbreviation:  Pharmacotherapy     Publication Date:  2002 Dec 
Date Detail:
Created Date:  2002-12-23     Completed Date:  2003-03-19     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8111305     Medline TA:  Pharmacotherapy     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1533-40     Citation Subset:  IM    
Department of Pharmacy Practice and Pharmacy Administration, University of the Sciences in Philadelphia, Philadelphia College of Pharmacy, 600 South 43rd Street, Philadelphia, PA 19104, USA.
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MeSH Terms
Antihypertensive Agents / pharmacology,  therapeutic use*
Blood Pressure / drug effects,  physiology
Chi-Square Distribution
Hospitals, Veterans / statistics & numerical data*
Hypertension / drug therapy*,  physiopathology,  psychology
Middle Aged
Outpatient Clinics, Hospital / statistics & numerical data*
Patient Compliance / psychology,  statistics & numerical data
Patient Satisfaction / statistics & numerical data
Pharmacists / psychology,  statistics & numerical data*
Pharmacy Administration / methods*,  statistics & numerical data
Prospective Studies
Quality of Life / psychology
Statistics, Nonparametric
Reg. No./Substance:
0/Antihypertensive Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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