Document Detail


Improving biosensor analysis.
MedLine Citation:
PMID:  10556875     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The quality of optical biosensor data must be improved in order to characterize the mechanism and rate constants associated with molecular interactions. Many of the artifacts associated with binding data can be minimized or eliminated by designing the experiment properly, collecting data under optimum conditions and processing the data with reference surfaces. It is possible to globally fit high-quality biosensor data with simple bimolecular reaction models, which validates the technology as a biophysical tool for interaction analysis.
Authors:
D G Myszka
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of molecular recognition : JMR     Volume:  12     ISSN:  0952-3499     ISO Abbreviation:  J. Mol. Recognit.     Publication Date:    1999 Sep-Oct
Date Detail:
Created Date:  2000-04-14     Completed Date:  2000-04-14     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  9004580     Medline TA:  J Mol Recognit     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  279-84     Citation Subset:  IM    
Copyright Information:
Copyright 1999 John Wiley & Sons, Ltd.
Affiliation:
Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84132, USA. dmyszka@hci.utah.edu
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MeSH Terms
Descriptor/Qualifier:
Biosensing Techniques / instrumentation,  methods*,  standards
Interleukin-2 / metabolism
Receptors, Interleukin-2 / metabolism
Grant Support
ID/Acronym/Agency:
2 P30 CA42014-12/CA/NCI NIH HHS
Chemical
Reg. No./Substance:
0/Interleukin-2; 0/Receptors, Interleukin-2

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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