Document Detail

Improving antenatal care to prevent adverse pregnancy outcomes caused by syphilis.
MedLine Citation:
PMID:  22004031     Owner:  NLM     Status:  In-Data-Review    
Evaluation of: Hawkes S, Matin N, Broutet N, Low N. Effectiveness of interventions to improve screening for syphilis in pregnancy: a systematic review and meta-analysis. Lancet Infect. Dis. 11(9), 684-691 (2011). Untreated maternal syphilis continues to be an important risk factor for adverse pregnancy outcomes in many developing countries, resulting in spontaneous abortion, stillbirth, premature delivery or perinatal death. In this systematic review and meta-analysis, Hawkes et al. review the effectiveness of interventions to increase the uptake of syphilis screening and treatment in pregnancy. The ten studies they review, published between 1986 and 2008, have a total sample size of more than 41,000. Overall, they showed that interventions to improve the uptake of antenatal screening for syphilis in pregnancy could reduce the syphilis-attributable incidence of stillbirth and perinatal death by 50%. As prevention of congenital syphilis costs less than US$1.50 per woman screened, the investment to scale up antenatal screening programs would be cost effective, would significantly improve pregnancy outcomes and reduce neonatal mortality.
Xiang-Sheng Chen; Rosanna W Peeling; Yue-Ping Yin; David Mabey
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Future microbiology     Volume:  6     ISSN:  1746-0921     ISO Abbreviation:  Future Microbiol     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2011-10-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101278120     Medline TA:  Future Microbiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  1131-4     Citation Subset:  IM    
National Center for STD Control & Chinese Academy of Medical Sciences & Peking Union Medical College Institute of Dermatology, 12 Jiangwangmiao Street, Nanjing 210042, China.
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