Document Detail


Improving Lipid Profile in Hypercholesterolemia-induced Rabbit by Supplementation of Germinated Brown Rice.
MedLine Citation:
PMID:  21682316     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
It is imperative that there be a diet designed specifically to improve lipid profile in order to impede the progress of atherosclerosis. Since rice is a staple food in Asia, it will be chosen as diet of interest. This study sets out to discover whether consumption of different processed rice diet may result in the change of lipid profile. The experiment was done on male New Zealand white rabbits after 10 weeks of treatment with diet containing 0.5% cholesterol. The experimental diets include white rice (WR), brown rice (BR) and germinated brown rice (GBR). Among them, those fed a GBR diet demonstrated significantly lower level of total cholesterol (TC), low density lipoprotein (LDL), LDL/HDL, atherogenic index (AI) and higher level of high density lipoprotein (HDL). Result from atherosclerotic plaque assessment further support the findings. The level of malondialdehyde (MDA), which act as one of the indicator for oxidative stress was also reduced by GBR diet. The positive change in lipid profile in the rabbit fed with GBR appeared to correspond with the higher amount of γ-oryzanol, tocopherol and monounsaturated fatty acid (MUFA) content.
Authors:
Norhaizan Mohd Esa; Khairul Kamilah Abdul Kadir; Zulkhairi Amom; Azrina Azlan
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-6-18
Journal Detail:
Title:  Journal of agricultural and food chemistry     Volume:  -     ISSN:  1520-5118     ISO Abbreviation:  -     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-6-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0374755     Medline TA:  J Agric Food Chem     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
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