Document Detail

Improvements in liver diseases evaluation using transient elastography for obese patients.
MedLine Citation:
PMID:  18529322     Owner:  NLM     Status:  In-Data-Review    
Transient elastography (Fibroscan((R)), Echosens, Paris, France) is a non invasive and rapid technique used to assess liver fibrosis by measuring liver stiffness. Clinical interest of liver stiffness measurement using Fibroscan((R)) has been demonstrated for chronic liver diseases in adult patients. Clinically, the liver stiffness evaluation can be tricky in obese patients due to their large subcutaneous fat thickness. Obesity is a growing public health concern which requires dedicated liver evaluation procedures due to the patients' morphology andor the specific diseases associated with obesity. Our study aims to show how Fibroscan((R)) can adapt for liver diseases evaluation in obese patients. Clinical adaptations dedicated to over-weighted patients are shown: ultrasound guidance procedure, development of a dedicated probe for patients with a large subcutaneous fat thickness, development of new algorithms based on attenuation of both ultrasonic and shear waves. Performance is assessed and clinical interest of each adaptation is discussed in over-weighted, obese and morbid obese patients (body mass index greater than 25). These new procedures dedicated to obese patients improve liver diseases assessment using Fibroscan((R)).
Magali Sasso; Veronique Miette; Laurent Sandrin
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of the Acoustical Society of America     Volume:  123     ISSN:  1520-8524     ISO Abbreviation:  J. Acoust. Soc. Am.     Publication Date:  2008 May 
Date Detail:
Created Date:  2008-06-05     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7503051     Medline TA:  J Acoust Soc Am     Country:  United States    
Other Details:
Languages:  eng     Pagination:  3000     Citation Subset:  IM    
Echosens, R&D department, 153 avenue d'Italie, 75013 Paris, France,
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