Document Detail

Improvements in heart rate variability with exercise therapy.
MedLine Citation:
PMID:  20548976     Owner:  NLM     Status:  MEDLINE    
Heart rate variability (HRV) is a noninvasive, practical and reproducible measure of autonomic nervous system function. A heart rate that is variable and responsive to demands is believed to bestow a survival advantage, whereas reduced HRV may be associated with poorer cardiovascular health and outcomes. In recent years, many researchers have investigated the prognostic implications of HRV in a variety of clinical populations. Evidence suggests that reduced HRV has prognostic significance for individuals with myocardial infarction, chronic heart failure, unstable angina and diabetes mellitus. Interventions to increase HRV, such as exercise therapy, have also been examined. The findings of the present review suggest that exercise therapy may improve HRV in myocardial infarction, chronic heart failure and revascularization patients by increasing vagal tone and decreasing sympathetic activity. One hypothesis is that a shift toward greater vagal modulation may positively affect the prognosis of these individuals. While the underlying mechanisms by which exercise training improves vagal modulation are speculative at present, angiotensin II and nitric oxide may be potential mediators.
Faye S Routledge; Tavis S Campbell; Judith A McFetridge-Durdle; Simon L Bacon
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  The Canadian journal of cardiology     Volume:  26     ISSN:  1916-7075     ISO Abbreviation:  Can J Cardiol     Publication Date:    2010 Jun-Jul
Date Detail:
Created Date:  2010-06-15     Completed Date:  2010-07-15     Revised Date:  2011-07-28    
Medline Journal Info:
Nlm Unique ID:  8510280     Medline TA:  Can J Cardiol     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  303-12     Citation Subset:  IM    
Dalhousie University, School of Nursing, Halifax, Nova Scotia, Canada.
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MeSH Terms
Autonomic Nervous System / physiopathology*
Cardiovascular Diseases / physiopathology*,  rehabilitation*
Exercise Therapy / methods*
Heart Rate / physiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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