Document Detail

Improvements in daily functioning after deep brain stimulation of the thalamus for intractable tremor.
MedLine Citation:
PMID:  9686776     Owner:  NLM     Status:  MEDLINE    
Deep brain stimulation (DBS) of the thalamus reduces tremor in patients with essential tremor (ET). However, few studies have determined the degree of improvement in daily functioning associated with DBS. We developed a self-report Tremor Activities of Daily Living Scale (TADLS) to compare daily functioning with the stimulator turned on and off. Patients rated their performance on the 30 items of the TADLS with the stimulator turned off and then on. They also performed 10 activities under the supervision of a clinician who rated their functional ability with stimulation off and then on. There was a 58% improvement in self-rated TADLS scores in patients with DBS with the stimulator on compared with stimulation off. When activities were rated by the clinician, the average improvement in functioning with the stimulator on was 54%. There were reasonably high correlations between patient and clinician ratings of functioning. ET patients have a marked improvement in daily functioning with thalamic DBS.
K E Lyons; R Pahwa; K L Busenbark; A I Tröster; S Wilkinson; W C Koller
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Movement disorders : official journal of the Movement Disorder Society     Volume:  13     ISSN:  0885-3185     ISO Abbreviation:  Mov. Disord.     Publication Date:  1998 Jul 
Date Detail:
Created Date:  1998-10-28     Completed Date:  1998-10-28     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8610688     Medline TA:  Mov Disord     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  690-2     Citation Subset:  IM    
Department of Neurology, University of Kansas Medical Center, Kansas City 66160-7314, USA.
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MeSH Terms
Activities of Daily Living / classification*
Dominance, Cerebral / physiology
Electric Stimulation Therapy*
Electrodes, Implanted
Neurologic Examination
Quality of Life
Thalamus / physiopathology*
Tremor / physiopathology,  therapy*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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