| Improvements in body composition, glucose tolerance, and insulin action induced by increasing energy expenditure or decreasing energy intake. | |
| | |
MedLine Citation:
|
PMID: 17374683 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Increases in exercise energy expenditure without compensatory changes in food intake (EX) and restriction of calorie intake (CR) both decrease body weight and fat mass, which, in turn, improve glucoregulatory function. However, EX may provide greater benefits than can be provided through CR. Therefore, our study hypothesis was that weight loss through EX reduces visceral abdominal fat and improves glucoregulation to a greater extent than does similar weight loss through CR. Forty-eight sedentary 50- to 60-y-old men and women, most of whom were overweight, underwent 12 mo of EX, CR, or a healthy lifestyle control period. Body composition was assessed by dual-energy x-ray absorptiometry and by magnetic resonance imaging. Indices of glucoregulatory function were determined by oral glucose tolerance test and were measured > or =48 h after the last exercise bout in the EX group. Body weight, total fat mass, and visceral fat volume decreased similarly in the EX and CR groups but did not change in the HL group. Likewise, insulin sensitivity index and the oral glucose tolerance test glucose and insulin areas under the curve improved similarly in the EX and CR groups and remained unchanged in the HL group. In conclusion, weight losses induced by exercise and by CR are effective means for improving glucose tolerance and insulin action in nonobese, healthy, middle-aged men and women; however, it does not appear that exercise training-induced weight loss results in greater improvements than those that result from CR. |
| | |
Authors:
|
Edward P Weiss; John O Holloszy |
Related Documents
:
|
8590883 - The use of ultrasonography for the detection of retained wooden foreign bodies in the f... 11915933 - Effect of aging on glucose and lipid metabolism during endurance exercise. 12230293 - Clinical approach to urinary incontinence: a comparison between internists and geriatri... |
Publication Detail:
|
Type: Journal Article; Research Support, N.I.H., Extramural |
Journal Detail:
|
Title: The Journal of nutrition Volume: 137 ISSN: 0022-3166 ISO Abbreviation: J. Nutr. Publication Date: 2007 Apr |
Date Detail:
|
Created Date: 2007-03-21 Completed Date: 2007-05-04 Revised Date: 2011-02-21 |
Medline Journal Info:
|
Nlm Unique ID: 0404243 Medline TA: J Nutr Country: United States |
Other Details:
|
Languages: eng Pagination: 1087-90 Citation Subset: IM |
Affiliation:
|
Division of Geriatrics and Nutritional Sciences, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Absorptiometry, Photon Body Composition / physiology* Body Weight Energy Intake / physiology* Energy Metabolism / physiology* Female Glucose / physiology* Glucose Tolerance Test Humans Insulin / physiology* Life Style Magnetic Resonance Imaging Male Middle Aged Overweight Physical Education and Training Postmenopause |
| Grant Support | |
ID/Acronym/Agency:
|
AG00078/AG/NIA NIH HHS; AG20487/AG/NIA NIH HHS; DK20579/DK/NIDDK NIH HHS; DK56341/DK/NIDDK NIH HHS; P30 DK056341-06/DK/NIDDK NIH HHS; P30 DK056341-07/DK/NIDDK NIH HHS; RR00036/RR/NCRR NIH HHS |
| Chemical | |
Reg. No./Substance:
|
11061-68-0/Insulin; 50-99-7/Glucose |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Starving for life: what animal studies can and cannot tell us about the use of caloric restriction t...
Next Document: Designing snacks to address micronutrient deficiencies in rural Kenyan schoolchildren.