Document Detail


Improvement with disodium cromoglycate of neutrophil phagocytosis and respiratory burst activity in a patient with hyperimmunoglobulin E syndrome.
MedLine Citation:
PMID:  9860246     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report a case of hyperimmunoglobulin E syndrome (HIE) complicated by neutrophil deficiency which was successfully treated with oral administration of disodium cromoglycate. A 48-year-old Japanese man with HIE developed Streptococcus pneumoniae meningitis. Laboratory tests after the meningitis revealed persistent neutropenia (300-800/mm3) and defects of phagocytosis and bacterial killing by neutrophils. Administration of disodium cromoglycate was started, and neutrophil counts gradually increased to 1200-1600/mm3. The impaired neutrophil activities returned to normal. The patient improved clinically; during the 2-year treatment, he had only two brief episodes of the common cold. Disodium cromoglycate may have potential clinical use in the treatment of cases of HIE even with neutrophil deficiency.
Authors:
K Kojima; Y Inoue; Y Katayama; M Kataoka; K Sunami; S Fukuda; T Sezaki; E Omoto; M Harada
Related Documents :
10830046 - Neonatal empyema thoracis.
5571836 - The importance of group b streptococci as human pathogens in the british isles.
21941136 - Presentation and outcomes for children with bone marrow necrosis and acute lymphoblasti...
11017846 - Veillonella parvula meningitis: case report and review of veillonella infections.
15471026 - Stump appendicitis: case report and review.
10081566 - An unusual cavity within the styloid process.
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Allergy     Volume:  53     ISSN:  0105-4538     ISO Abbreviation:  Allergy     Publication Date:  1998 Nov 
Date Detail:
Created Date:  1999-02-25     Completed Date:  1999-02-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7804028     Medline TA:  Allergy     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  1101-3     Citation Subset:  IM    
Affiliation:
Department of Medicine, National Okayama Hospital, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Cromolyn Sodium / therapeutic use*
Hematologic Agents / therapeutic use*
Humans
Job's Syndrome / drug therapy*
Male
Meningitis, Bacterial / complications,  microbiology
Middle Aged
Neutropenia / drug therapy,  etiology
Neutrophils / drug effects*,  physiology
Phagocytosis / drug effects*,  physiology
Pulmonary Ventilation / drug effects
Respiratory Burst / drug effects*
Streptococcus pneumoniae
Chemical
Reg. No./Substance:
0/Hematologic Agents; 15826-37-6/Cromolyn Sodium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Prevalence of occupational asthma among automobile and furniture painters in the center of Eskisehir...
Next Document:  Colocalization of tight junction proteins, occludin and ZO-1, and glucose transporter GLUT1 in cells...