Document Detail


Improvement of temporal and dynamic subtraction images on abdominal CT using 3D global image matching and nonlinear image warping techniques.
MedLine Citation:
PMID:  17951855     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Accurate registration of the corresponding non-enhanced and arterial-phase CT images is necessary to create temporal and dynamic subtraction images for the enhancement of subtle abnormalities. However, respiratory movement causes misregistration at the periphery of the liver. To reduce these misregistration errors, we developed a temporal and dynamic subtraction technique to enhance small HCC by 3D global matching and nonlinear image warping techniques. The study population consisted of 21 patients with HCC. Using the 3D global matching and nonlinear image warping technique, we registered current and previous arterial-phase CT images or current non-enhanced and arterial-phase CT images obtained in the same position. The temporal subtraction image was obtained by subtracting the previous arterial-phase CT image from the warped current arterial-phase CT image. The dynamic subtraction image was obtained by the subtraction of the current non-enhanced CT image from the warped current arterial-phase CT image. The percentage of fair or superior temporal subtraction images increased from 52.4% to 95.2% using the new technique, while on the dynamic subtraction images, the percentage increased from 66.6% to 95.2%. The new subtraction technique may facilitate the diagnosis of subtle HCC based on the superior ability of these subtraction images to show nodular and/or ring enhancement.
Authors:
E Okumura; S Sanada; M Suzuki; A Takemura; O Matsui
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Publication Detail:
Type:  Journal Article     Date:  2007-10-16
Journal Detail:
Title:  Physics in medicine and biology     Volume:  52     ISSN:  0031-9155     ISO Abbreviation:  Phys Med Biol     Publication Date:  2007 Nov 
Date Detail:
Created Date:  2007-10-22     Completed Date:  2008-01-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0401220     Medline TA:  Phys Med Biol     Country:  England    
Other Details:
Languages:  eng     Pagination:  6461-74     Citation Subset:  IM    
Affiliation:
Department of Radiological Technology, Graduate School of Medical Sciences, Kanazawa University, 5-11-80 Kodatsuno, Kanazawa 920-0942, Japan.
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MeSH Terms
Descriptor/Qualifier:
Aged
False Positive Reactions
Female
Humans
Imaging, Three-Dimensional / methods*
Liver / pathology*
Male
Middle Aged
Models, Statistical
Movement
Radiographic Image Interpretation, Computer-Assisted / methods*
Respiration*
Subtraction Technique
Time Factors
Tomography, X-Ray Computed / methods*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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