Document Detail

Improvement of sperm production in subfertile boars by Cordyceps militaris supplement.
MedLine Citation:
PMID:  17708629     Owner:  NLM     Status:  MEDLINE    
Cordyceps species have been traditionally used for the enhancement of sexual function, however, there is few direct evidence to prove this. We investigated the spermatogenic effect of Cordyceps militaris (CM) by supplementation with CM mycelium to subfertile boars. Seventeen Duroc and 12 Landrace boars (29 to 40 months old) were selected to feed with regular diet (control groups, n = 8 and 6, respectively) or diet supplemented with CM mycelium (treatment groups, n = 9 and 6, respectively) for 2 months. Semen was collected once a week. The quality of fertile sperm (normally greater than 62% of motility and 70% of normal morphology) and the quantity (semen volume, and total sperm number) were compared in these boars. The result showed that sperm production was enhanced significantly at the end of first month (p < 0.05), peaked at the second month (p < 0.01) of supplementation with CM and was maintained for 2 weeks after stopping the treatment (p < 0.01). Plasma cordycepin concentration was detected in boars supplemented with CM but not in the controls. More importantly, the percentages of motile sperm cells and sperm morphology were also improved significantly in most of treated boars during the second month of supplementation (p < 0.01) and 2 weeks after the treatment (p < 0.05) as compared to their initial values. These results indicate that supplementation with CM mycelium improves sperm quality and quantity in subfertile boars and may partly support the role of Cordyceps in sexual enhancement.
Wen-Hung Lin; Ming-Ta Tsai; Yuh-Shuen Chen; Rolis Chien-Wei Hou; Hsiao-Fang Hung; Ching-Hsiao Li; Hsin-Kai Wang; Min-Nan Lai; Kee-Ching G Jeng
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The American journal of Chinese medicine     Volume:  35     ISSN:  0192-415X     ISO Abbreviation:  Am. J. Chin. Med.     Publication Date:  2007  
Date Detail:
Created Date:  2007-08-21     Completed Date:  2007-11-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7901431     Medline TA:  Am J Chin Med     Country:  Singapore    
Other Details:
Languages:  eng     Pagination:  631-41     Citation Subset:  IM    
Fo Guang College of Humanities and Social Sciences, Ilan, Taiwan.
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MeSH Terms
Dietary Supplements
Drugs, Chinese Herbal / pharmacology,  therapeutic use*
Infertility, Male / drug therapy*,  physiopathology,  veterinary
Phytotherapy / methods
Sperm Count
Sperm Motility / drug effects,  physiology
Spermatogenesis / drug effects*,  physiology
Spermatozoa / pathology
Sus scrofa
Reg. No./Substance:
0/Drugs, Chinese Herbal

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