Document Detail

Improvement of semen quality by nocturnal scrotal cooling in oligozoospermic men with a history of testicular maldescent.
MedLine Citation:
PMID:  15811070     Owner:  NLM     Status:  MEDLINE    
For infertile men with a history of testicular maldescent only few therapeutic options exist beside assisted reproduction. The aim of our study was to evaluate the influence of nocturnal scrotal cooling on semen quality in such patients presenting with oligozoospermia. Twenty infertile men with a history of testicular maldescent and oligozoospermia were included for nocturnal scrotal cooling over 12 weeks for every night. To increase nocturnal periscrotal air circulation we used a membrane pump connected via plastic tubes to receptacles placed in both groins. Semen analysis was performed at the beginning of the cooling period and at weeks 4, 8 and 12. Another 20 infertile patients with a history of testicular maldescent and oligozoospermia were followed without specific treatment and served as a retrospectively built control group. Scrotal cooling at night by means of a perigenital air stream resulted in a scrotal temperature drop by 0.8 degrees C (median). A significant increase in sperm concentration and total sperm count was achieved by nocturnal cooling after 8 weeks (p < 0.01; p < 0.05; respectively) and 12 weeks (p < 0.01; p < 0.01; respectively). The improvement of sperm motility and sperm morphology was statistically insignificant. The present study suggests nocturnal scrotal cooling as a therapeutic option to improve semen quality. In a further controlled prospective study the influence on pregnancy rates should be evaluated.
A Jung; W-B Schill; H-C Schuppe
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of andrology     Volume:  28     ISSN:  0105-6263     ISO Abbreviation:  Int. J. Androl.     Publication Date:  2005 Apr 
Date Detail:
Created Date:  2005-04-06     Completed Date:  2005-06-24     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  8000141     Medline TA:  Int J Androl     Country:  England    
Other Details:
Languages:  eng     Pagination:  93-8     Citation Subset:  IM    
Center of Dermatology and Andrology, Justus Liebig University, D-35392 Giessen, Germany.
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MeSH Terms
Body Temperature
Cold Temperature*
Cryptorchidism / physiopathology*,  therapy
Oligospermia / physiopathology*,  therapy
Retrospective Studies
Scrotum / physiopathology*
Semen / cytology,  physiology*
Sperm Count
Sperm Motility

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