Document Detail

Improvement of the probiotic effect of micro-organisms by their combination with maltodextrins, fructo-oligosaccharides and polyunsaturated fatty acids.
MedLine Citation:
PMID:  12215187     Owner:  NLM     Status:  MEDLINE    
Probiotics could represent an effective alternative to the use of synthetic substances in nutrition and medicine. The data concerning the efficacy of probiotics are often contradictory. This paper focuses on the enhancement of the efficacy of probiotics by their combination with synergistically acting components of natural origin. Maltodextrins can be obtained by enzymatic hydrolysis of starch and are suitable for consumption. Administration of Lactobacillus paracasei together with maltodextrin decreased the number of Escherichia coli colonising the jejunal mucosa of gnotobiotic piglets by 1 logarithm compared to the control group. Fructo-oligosaccharides (FOS) are naturally occurring oligosaccharides, mainly of plant origin. L. paracasei administered in combination with FOS significantly increased counts of Lactobacillus spp., Bifidobacterium spp., total anaerobes and total aerobes compared to the control group as well as the L. paracasei group. It also significantly decreased Clostridium and Enterobacterium counts in the faeces of the weanling piglets compared with the control group. Dietary lipids influence the gastrointestinal microbiota and specifically the population of lactic acid bacteria. In gnotobiotic piglets the oral administration of an oil containing polyunsaturated fatty acids (PUFA) significantly increased the number of L. paracasei adhering to jejunal mucosa compared to the control group. Our results showed that maltodextrin KMS X-70 and PUFA can be used to enhance the effect of probiotic micro-organisms in the small intestine, and similarly FOS enhance the effect of probiotic micro-organisms in the large intestine.
A Bomba; R Nemcová; S Gancarcíková; R Herich; P Guba; D Mudronová
Related Documents :
16348117 - Production of bakers' yeast in cheese whey ultrafiltrate.
9190127 - Effect of lactic acid on water content and osmotic fragility of erythrocytes in vivo.
16171677 - Production of d-lactic acid from defatted rice bran by simultaneous saccharification an...
6259717 - Effect of macromolecules on adherence of streptococcus mutans.
19337627 - 24-hour ambulatory ph-metry in patients with refractory heartburn: a prospective study.
11093917 - Effect of hyperinsulinemia on amino acid utilization in the ovine fetus.
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The British journal of nutrition     Volume:  88 Suppl 1     ISSN:  0007-1145     ISO Abbreviation:  Br. J. Nutr.     Publication Date:  2002 Sep 
Date Detail:
Created Date:  2002-09-06     Completed Date:  2002-11-08     Revised Date:  2006-04-13    
Medline Journal Info:
Nlm Unique ID:  0372547     Medline TA:  Br J Nutr     Country:  England    
Other Details:
Languages:  eng     Pagination:  S95-9     Citation Subset:  IM    
Research Institute of Veterinary Medicine, Hlinkova 1/A, 040 01, Slovak Republic.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Dietary Carbohydrates / therapeutic use*
Dietary Fats, Unsaturated / therapeutic use*
Fatty Acids, Unsaturated / therapeutic use
Intestines / microbiology*
Oligosaccharides / therapeutic use
Polysaccharides / therapeutic use
Probiotics / therapeutic use*
Reg. No./Substance:
0/Dietary Carbohydrates; 0/Dietary Fats, Unsaturated; 0/Fatty Acids, Unsaturated; 0/Idolax; 0/Oligosaccharides; 0/Polysaccharides; 9050-36-6/maltodextrin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Diet and cancer: assessing the risk.
Next Document:  Primary pulmonary hypertension and cor pulmonale.