| Improvement of metabolic syndrome markers through altitude specific hiking vacations. | |
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MedLine Citation:
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PMID: 16840826 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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To study the influence of a 3-week hiking vacation at moderate (1700 m) and low altitude (LA) (200 m) on key-markers of the metabolic syndrome, 71 male volunteers (age 36-66 yr old) with the metabolic syndrome [according to the National Cholesterol Education Program's Adult Treatment Panel III (NCEP-ATP III) - or World Health Organization (WHO) - definition] participated in the study and were randomly assigned into a moderate altitude (MA) group (1700 m, no. 36) and a low altitude (LA) group (200 m, no. 35). The 3-week vacation program included 12 moderate- intensity guided hiking tours [4 times/week, 55-65% heart rate maximum (HRmax)] with a total exercise time of 29 h plus moderate recreational activities. Both study groups had a comparable and balanced nutrition with no specific dietary restrictions. Anthropometric, metabolic and cardiovascular parameters were measured 10-14 days before vacation, several times during the 3-week vacation, 7-10 days and 6-8 weeks after return. All participants tolerated the vacation without any adverse effects. Body weight, body fat, waist-circumference, fasting glucose, total cholesterol, LDL-cholesterol (LDL-C), plasma fibrinogen, resting systolic and diastolic blood pressure were significantly decreased over time in both study groups. In the LA group, fasting insulin and homeostasis model assessment (HOMA)-index were significantly decreased one week after return. Relative cycle ergometry performance was significantly increased after return compared to baseline. In both study groups, waist-to-hip ratio (WHR), 2-h oral glucose tolerance test (OGTT), HDL-cholesterol (HDL-C), and triglycerides remained unchanged. The 3-week vacation intervention at moderate and LA had a positive influence on all key-markers of the metabolic syndrome. No clinically relevant differences could be detected between the study groups. A hiking vacation at moderate and LA can be recommended for people with stable, controlled metabolic and cardiovascular risk factors. |
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Authors:
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S Greie; E Humpeler; H C Gunga; E Koralewski; A Klingler; M Mittermayr; D Fries; M Lechleitner; H Hoertnagl; G Hoffmann; G Strauss-Blasche; W Schobersberger |
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Publication Detail:
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Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of endocrinological investigation Volume: 29 ISSN: 0391-4097 ISO Abbreviation: J. Endocrinol. Invest. Publication Date: 2006 Jun |
Date Detail:
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Created Date: 2006-07-14 Completed Date: 2006-08-24 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7806594 Medline TA: J Endocrinol Invest Country: Italy |
Other Details:
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Languages: eng Pagination: 497-504 Citation Subset: IM |
Affiliation:
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University for Health Sciences, Medical Informatics and Technology Tyrol, Institute for Leisure, Travel and Alpine Medicine, A-6060 Hall in Tirol, Austria. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Altitude* Blood Glucose / metabolism Blood Pressure / physiology Body Composition / physiology Cholesterol / blood Exercise Test Fibrinogen / metabolism Humans Insulin / blood Leisure Activities* Male Metabolic Syndrome X / metabolism*, therapy* Middle Aged Triglycerides / blood Walking* |
| Chemical | |
Reg. No./Substance:
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0/Blood Glucose; 0/Triglycerides; 11061-68-0/Insulin; 57-88-5/Cholesterol; 9001-32-5/Fibrinogen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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