| Improvement of intra-epidermal nerve fiber density in hypothyroidism after L-thyroxine therapy. | |
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MedLine Citation:
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PMID: 22630564 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Hypothyroidism may induce a wide range of neurological complaints, frequently described in the past, but nowadays rarely reported due to earlier diagnosis and treatment. By investigating a series of neurologically asymptomatic, untreated patients with hypothyroidism, either overt (OH) or subclinical (SH), we found in 11% of them an asymptomatic polyneuropathy, as assessed by conventional neurophysiological studies (1) . In the same group of patients, using a skin biopsy technique, we observed a significant reduction of intra-epidermal nerve fiber (IENF) density with a prevalence of 60% and 25% in OH and SH, respectively © 2012 Blackwell Publishing Ltd. |
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Authors:
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Flavia Magri; Michelangelo Buonocore; Antonella Camera; Valentina Capelli; Antonio Oliviero; Mario Rotondi; Anna Gatti; Luca Chiovato |
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Publication Detail:
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Type: LETTER Date: 2012-5-27 |
Journal Detail:
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Title: Clinical endocrinology Volume: - ISSN: 1365-2265 ISO Abbreviation: - Publication Date: 2012 May |
Date Detail:
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Created Date: 2012-5-28 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0346653 Medline TA: Clin Endocrinol (Oxf) Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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© 2012 Blackwell Publishing Ltd. |
Affiliation:
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Unit of Internal Medicine and Endocrinology, Fondazione Salvatore Maugeri I.R.C.C.S., University of Pavia, Pavia, Italy. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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