Document Detail


Improvement in skin wrinkles with use of a preparation containing human growth factors and hyaluronic acid serum.
MedLine Citation:
PMID:  25260051     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Abstract BACKGROUND Skin aging is accompanied by wrinkle formation. At some sites, as the periorbital skin, this is a relatively early phenomenon. OBJECTIVE We evaluated the anti-wrinkle effect of a preparation containing human growth factor and hyaluronic acid serum on periorbital wrinkles (crow's feet). MATERIALS AND METHODS In all, 23 Korean women (age range: 39-59 years), who were not pregnant, nursing, or undergoing any concurrent therapy were enrolled in this study. All the patients completed an 8-week trial of twice daily application of human growth factor and hyaluronic acid serum on the entire face. Efficacy was based on a global photodamage score, photographs, and image analysis using replicas and visiometer analysis every 4 weeks. The standard wrinkle and roughness parameters used in assessing skin by visiometer were calculated and statistically analyzed. RESULTS Periorbital wrinkles were significantly improved after treatment, with improvements noted both by physician assessment and visiometer analysis. CONCLUSION Topical application of human growth factor and hyaluronic acid was beneficial in reducing periorbital wrinkles.
Authors:
Do Hyun Lee; In Young Oh; Kyo Tan Koo; Jang Mi Suk; Sang Wook Jung; Jin Oh Park; Beom Joon Kim; Yoo Mi Choi
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-9-26
Journal Detail:
Title:  Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology     Volume:  -     ISSN:  1476-4180     ISO Abbreviation:  J Cosmet Laser Ther     Publication Date:  2014 Sep 
Date Detail:
Created Date:  2014-9-26     Completed Date:  -     Revised Date:  2014-9-27    
Medline Journal Info:
Nlm Unique ID:  101136419     Medline TA:  J Cosmet Laser Ther     Country:  -    
Other Details:
Languages:  ENG     Pagination:  1-17     Citation Subset:  -    
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