| Improvement in the plasma omega-3 index by the use of a fish oil-enriched spread. | |
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MedLine Citation:
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PMID: 18772586 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: The main aim of this pilot study was to determine whether the omega-3 status can be improved by the use of a fish oil-enriched spread in a regular diet. METHODS: The study started with an open arm where the participants consumed their regular diets followed by a randomized placebo-controlled arm with the inclusion of a spread which was either fish oil enriched or not (control). After each period,the fatty acid composition of red blood cell (RBC) and plasma phospholipids was determined by standard procedures and the sum of eicosapentaenoic and docosahexaenoic acid calculated. t tests were performed to calculate the significance. The first-order linear model was used to calculate correlations between selected parameters. RESULTS: When the patients were on their usual diets, a strong correlation was found between the omega-3 index based on RBCs and plasma.In the group consuming the fish oil-enriched spread, the omega-3 index based on both RBCs and plasma was significantly higher after 3 weeks of intervention. This was not the case after intervention with the control spread. CONCLUSION: Inclusion of reasonable amounts of a fish oil-enriched spread in an otherwise regular diet can be sufficient for obtaining a significant increase in omega-3 index. |
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Authors:
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Guy De Groote; André De Laporte; Goedele Dhondt; Armand Christophe |
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Publication Detail:
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Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't Date: 2008-09-05 |
Journal Detail:
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Title: Annals of nutrition & metabolism Volume: 53 ISSN: 1421-9697 ISO Abbreviation: Ann. Nutr. Metab. Publication Date: 2008 |
Date Detail:
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Created Date: 2008-10-20 Completed Date: 2009-01-27 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8105511 Medline TA: Ann Nutr Metab Country: Switzerland |
Other Details:
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Languages: eng Pagination: 23-8 Citation Subset: IM |
Copyright Information:
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Copyright 2008 S. Karger AG, Basel. |
Affiliation:
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CRI Laboratories, Ghent-Zwijnaarde, Belgium. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Docosahexaenoic Acids / administration & dosage, blood Eicosapentaenoic Acid / administration & dosage, blood Erythrocyte Membrane / chemistry, metabolism Erythrocytes / chemistry*, metabolism Fatty Acids, Omega-3 / administration & dosage*, blood* Female Fish Oils / administration & dosage, chemistry* Food, Fortified* Humans Linear Models Male Phospholipids / blood, chemistry* Pilot Projects |
| Chemical | |
Reg. No./Substance:
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0/Fatty Acids, Omega-3; 0/Fish Oils; 0/Phospholipids; 1553-41-9/Eicosapentaenoic Acid; 25167-62-8/Docosahexaenoic Acids |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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