| Improvement in left ventricular ejection fraction and wall motion after successful recanalization of chronic coronary occlusions. | |
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MedLine Citation:
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PMID: 9519321 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIMS: This study assessed changes in left ventricular ejection fraction and regional radial shortening after successful angioplasty of chronic coronary occlusions. METHODS: We studied 95 patients with angina pectoris or exercise-induced ischaemia with a successfully recanalized chronic (median duration 4.3 months) coronary occlusion. Intracoronary stents were implanted in 71%. Left ventriculograms were obtained at baseline and after 6.7 +/- 1.4 months. Left ventricular ejection fraction and regional radial shortening were determined by a computer-assisted method. RESULTS: Left ventricular ejection fraction increased from 0.62 +/- 0.13 at baseline to 0.67 +/- 0.11 at follow-up (P < 0.001). The change in left ventricular ejection fraction in patients with a patent artery and in patients with reocclusion (n = 8) was 0.05 +/- 0.06 and 0.01 +/- 0.04, respectively (P = 0.04). Regional radial shortening in the territory of the recanalized artery increased by 16% (from 0.28 +/- 0.11 to 0.32 +/- 0.11, P < 0.001) in patients with a patent artery at follow-up, but was unchanged in patients with reocclusion. CONCLUSION: Long-term patency after recanalization of old, chronic coronary occlusions in patients with angina pectoris is associated with improvement in global and regional left ventricular function. This may be a result of recovery of hibernating myocardium and supports the strategy of recanalizing chronic coronary occlusions. |
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Authors:
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P A Sirnes; Y Myreng; P Mølstad; V Bonarjee; S Golf |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: European heart journal Volume: 19 ISSN: 0195-668X ISO Abbreviation: Eur. Heart J. Publication Date: 1998 Feb |
Date Detail:
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Created Date: 1998-04-30 Completed Date: 1998-04-30 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8006263 Medline TA: Eur Heart J Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 273-81 Citation Subset: IM |
Affiliation:
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Feiring Heart Clinic, Norway. psirnes@online.no |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Angioplasty, Transluminal, Percutaneous Coronary Chronic Disease Cohort Studies Coronary Disease / physiopathology*, therapy* Female Heart / physiopathology* Humans Male Middle Aged Myocardial Contraction / physiology* Recurrence Stents Stroke Volume / physiology* Treatment Outcome Ventricular Function, Left / physiology* |
| Comments/Corrections | |
Comment In:
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Eur Heart J. 1998 Feb;19(2):198-9
[PMID:
9519310
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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